Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13289069 | 0.96 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GSK3BL3MBTL3CDK2 | |
| SCHEMBL13121086 | 0.91 | GSK3B (0.52) | ALDH1A1SMN1; SMN2GSK3BL3MBTL3CDK2 | |
| SCHEMBL13121162 | 0.89 | GSK3B (0.52) | ALDH1A1SMN1; SMN2GSK3BL3MBTL3CDK2 | |
| SCHEMBL13289501 | 0.88 | ALDH1A1 (0.47) | ALDH1A1GSK3BCDK2KMT2A | |
| SCHEMBL13288964 | 0.88 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2GSK3BCDK2KMT2A | |
| SCHEMBL13288981 | 0.87 | CDK2 (0.46) | ALDH1A1SMN1; SMN2GSK3BCDK2 | |
| SCHEMBL13121286 | 0.87 | GSK3B (0.53) | ALDH1A1SMN1; SMN2GSK3BCDK2KMT2A | |
| SCHEMBL13289466 | 0.86 | GSK3B (0.43) | ALDH1A1SMN1; SMN2GSK3BCDK2KMT2A | |
| SCHEMBL13289301 | 0.85 | CDK2 (0.46) | ALDH1A1GSK3BCDK2KMT2A | |
| SCHEMBL13288997 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2GSK3BCDK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194058-A1 | Pyrazolopyrimidines suitable for the treatment of cancer diseases | SCHERING CORPORATION (US) | 2010-06-09 | — | — | EP | disclosed |