SCHEMBL13289028

SCHEMBL13289028

CN(c1ccc2c(c1)CCc1ccccc1-2)c1ccc2c(c1)CCc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.47
SRD5A2 P31213 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
CYP1A2 P05177 3/20 0.43
CYP2D6 P10635 3/20 0.43
HSD17B10 Q99714 3/20 0.43
CYP3A4 P08684 3/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CES1 P23141 1/20 0.42
SLC6A2 P23975 2/20 0.41
SLC22A1 O15245 1/20 0.41
CACNA1F O60840 1/20 0.41
NTRK1 P04629 1/20 0.41
ADRB2 P07550 1/20 0.41
RET P07949 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
ADRB1 P08588 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17264178 0.85 CYP1A2 (0.58) SRD5A2RAB9ANPC1CYP1A2CYP2D6
SCHEMBL17904143 0.80 CYP1A2 (0.54) SRD5A2RAB9ANPC1CYP1A2CYP2D6
SCHEMBL13475665 0.76 SRD5A1 (0.42) SRD5A1SRD5A2RAB9ANPC1CYP1A2
SCHEMBL19049725 0.74 RXRA (0.39) HSD17B10ADRA2ADRD2ADRA2BADRA2C
SCHEMBL4818156 0.74 CES1 (0.56) SRD5A1SRD5A2RAB9ANPC1CES1
SCHEMBL6853221 0.74 SRD5A1 (0.52) SRD5A1SRD5A2RAB9ANPC1HSD17B10
Dihydrophenanthrene SCHEMBL155991 0.73 CES1 (0.68) SRD5A1SRD5A2RAB9ANPC1CES1
Dihydrophenanthrene SCHEMBL30297028 0.73 CES1 (0.68) SRD5A1SRD5A2RAB9ANPC1CES1
Dihydrophenanthrene SCHEMBL29404495 0.73 CES1 (0.68) SRD5A1SRD5A2RAB9ANPC1CES1
SCHEMBL1639476 0.73 CYP1A2 (0.58) SRD5A2RAB9ANPC1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010068000-A2 ARYL AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME 주식회사 두산 (KR) 2010-06-17 WO disclosed