Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | KLK7 | P49862 | 2/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857149 | 0.90 | MAPT (0.58) | SYKCTSSCTSLKLK7KLK5 | |
| SCHEMBL12148814 | 0.87 | MAPT (0.62) | KLK7KLK5MAPTSIRT2CPB1 | |
| SCHEMBL30902797 | 0.87 | MAPT (0.62) | CTSSCTSLKLK7KLK5MAPT | |
| SCHEMBL5058975 | 0.87 | SYK (0.54) | SYKCTSSCTSLKLK7KLK5 | |
| SCHEMBL918813 | 0.87 | SYK (0.60) | SYKCTSSCTSLKLK7KLK5 | |
| SCHEMBL4958981 | 0.87 | SYK (0.60) | SYKCTSSCTSLKLK7KLK5 | |
| SCHEMBL1021938 | 0.87 | SYK (0.60) | SYKCTSSCTSLKLK7KLK5 | |
| SCHEMBL29579727 | 0.86 | LMNA (0.57) | SYKCTSSCTSLKLK7KLK5 | |
| SCHEMBL29579745 | 0.86 | LMNA (0.57) | SYKCTSSCTSLKLK7KLK5 | |
| SCHEMBL12296233 | 0.86 | SYK (0.58) | SYKCTSSCTSLKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727991-B2 | Substituted melanocortin receptor-specific single acyl piperazine compounds | PALATIN TECHNOLOGIES, INC. (US) | 2010-06-01 | — | — | US | disclosed |