Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932327 | 0.98 | OPRK1 (0.70) | OPRK1OPRM1 | |
| SCHEMBL18413115 | 0.94 | OPRK1 (0.75) | OPRK1OPRM1 | |
| SCHEMBL20363368 | 0.92 | OPRK1 (0.63) | OPRK1OPRM1 | |
| SCHEMBL17132155 | 0.92 | OPRK1 (0.73) | OPRK1OPRM1 | |
| SCHEMBL11931470 | 0.91 | OPRK1 (0.72) | OPRK1OPRM1 | |
| SCHEMBL11931972 | 0.91 | OPRK1 (0.69) | OPRK1OPRM1 | |
| SCHEMBL10316466 | 0.89 | OPRK1 (0.60) | OPRK1 | |
| SCHEMBL10316438 | 0.88 | OPRK1 (0.74) | OPRK1OPRM1 | |
| SCHEMBL21286632 | 0.88 | OPRK1 (0.74) | OPRK1OPRM1 | |
| SCHEMBL19249834 | 0.88 | OPRK1 (0.74) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727963-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2010-06-01 | — | — | US | disclosed |