Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.91 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316439 | 0.95 | OPRK1 (1.00) | OPRK1OPRM1 | |
| SCHEMBL18413105 | 0.94 | OPRK1 (0.98) | OPRK1OPRM1 | |
| SCHEMBL13290873 | 0.93 | OPRK1 (0.91) | OPRK1OPRM1 | |
| SCHEMBL13290851 | 0.92 | OPRK1 (0.91) | OPRK1OPRM1 | |
| SCHEMBL24360695 | 0.91 | OPRK1 (0.84) | OPRK1OPRM1 | |
| SCHEMBL13290872 | 0.91 | OPRK1 (0.76) | OPRK1OPRM1 | |
| SCHEMBL20784131 | 0.90 | OPRK1 (0.88) | OPRK1OPRM1 | |
| SCHEMBL10316435 | 0.88 | OPRK1 (1.00) | OPRK1OPRM1 | |
| SCHEMBL21219312 | 0.88 | OPRK1 (0.88) | OPRK1OPRM1 | |
| SCHEMBL21219324 | 0.88 | OPRK1 (0.90) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727963-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2010-06-01 | — | — | US | disclosed |