Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 15/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.42 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.42 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.42 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.42 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.42 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932315 | 0.96 | OPRK1 (0.79) | OPRK1SLC6A2KMT2AOPRM1OPRD1 | |
| SCHEMBL13290881 | 0.93 | OPRK1 (0.77) | OPRK1OPRM1 | |
| SCHEMBL13290867 | 0.91 | OPRK1 (0.78) | OPRK1OPRM1 | |
| SCHEMBL21886398 | 0.90 | OPRK1 (0.72) | OPRK1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL21286534 | 0.89 | OPRK1 (0.61) | OPRK1KMT2APSMB11PSMA7PSMB1 | |
| SCHEMBL10316378 | 0.89 | OPRK1 (0.84) | OPRK1OPRM1 | |
| SCHEMBL13290878 | 0.88 | OPRK1 (0.91) | OPRK1OPRM1 | |
| SCHEMBL21286624 | 0.87 | OPRK1 (0.81) | OPRK1OPRM1 | |
| SCHEMBL10316475 | 0.87 | OPRK1 (0.85) | OPRK1OPRM1 | |
| SCHEMBL12317858 | 0.87 | OPRK1 (0.58) | OPRK1KMT2APSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727963-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2010-06-01 | — | — | US | disclosed |