Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14257980 | 1.00 | KDM4E (0.56) | KDM4ELMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL9792723 | 0.89 | OPRM1 (0.51) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13163119 | 0.89 | OPRM1 (0.51) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21787342 | 0.89 | OPRM1 (0.51) | KDM4EOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18729767 | 0.79 | KDM4E (0.61) | KDM4ELMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL2426994 | 0.79 | KDM4E (0.61) | KDM4ELMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL17130391 | 0.79 | KDM4E (0.61) | KDM4ELMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL15068257 | 0.78 | KDM4E (0.89) | KDM4ELMNAALDH1A1CYP2D6CHRM3 | |
| SCHEMBL4913525 | 0.78 | KDM4E (0.54) | KDM4ELMNAOPRK1ALDH1A1ADRA2A | |
| SCHEMBL15067033 | 0.78 | KDM4E (0.89) | KDM4ELMNAALDH1A1CYP2D6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745413-B2 | Collection of traceable compounds and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-06-29 | — | — | US | disclosed |
| US-7745413-B2 | Collection of traceable compounds and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-06-29 | — | — | US | disclosed |
| US-20080176763-A1 | Collection of Traceable Compounds and Uses Thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-07-24 | — | — | US | disclosed |
| US-20080176763-A1 | Collection of Traceable Compounds and Uses Thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-07-24 | — | — | US | disclosed |
| EP-1756119-B1 | COLLECTION OF TRACEABLE COMPOUNDS AND USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2007-10-10 | — | — | EP | disclosed |