⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293510 | 1.00 | — | — | |
| SCHEMBL28168136 | 0.84 | CYP2D6 (1.00) | — | |
| SCHEMBL3134391 | 0.84 | CYP2D6 (1.00) | — | |
| SCHEMBL190067 | 0.84 | CYP2D6 (1.00) | — | |
| SCHEMBL213024 | 0.84 | CYP2D6 (1.00) | — | |
| Ammonia Solution, Strong SCHEMBL25317376 | 0.81 | CYP2D6 (0.92) | — | |
| Hydrochloric Acid SCHEMBL10880042 | 0.81 | CYP2D6 (0.92) | — | |
| Ammonia Solution, Strong SCHEMBL25317379 | 0.81 | CYP2D6 (0.92) | — | |
| SCHEMBL11135300 | 0.75 | ALDH1A1 (0.80) | — | |
| SCHEMBL11135303 | 0.75 | ALDH1A1 (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8974595-B2 | Dry composition comprising a binder and a modified vegetable oil | SIKA TECHNOLOGY AG (CH) | 2015-03-10 | — | — | US | disclosed |
| EP-2401241-B1 | DRY COMPOSITION COMPRISING A BINDER AND A SILICONE OIL | SIKA TECHNOLOGY AG (CH) | 2014-09-17 | — | — | EP | disclosed |
| EP-2401240-B1 | DRY COMPOSITION COMPRISING A BINDER AND A MODIFIED VEGETABLE OIL | SIKA TECHNOLOGY AG (CH) | 2014-09-03 | — | — | EP | disclosed |
| US-20140031334-A1 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-8598162-B2 | Derivatives of 4-piperazin-1-yl-4-benzo[B]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-12-03 | — | — | US | disclosed |
| WO-2012175373-A1 | SHEET‑MATERIAL COMPOSITE, USE OF THE SHEET‑MATERIAL COMPOSITE AND CREPE SHEET CONTAINING THE SHEET‑MATERIAL COMPOSITE | HUHTAMAKI FORCHHEIM ZWEIGNIEDERLASSUNG DER HUHTAMAKI DEUTSCHLAND GMBH & CO. KG (DE) | 2012-12-27 | — | — | WO | disclosed |
| EP-2287161-B1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMA CO LTD (JP) | 2012-05-09 | — | — | EP | disclosed |
| EP-2287162-B1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMA CO LTD (JP) | 2012-05-09 | — | — | EP | disclosed |
| EP-2284169-B1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMA CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |
| US-20120055373-A1 | DRY COMPOSITION COMPRISING A BINDER AND A MODIFIED VEGETABLE OIL | SIKA TECHNOLOGY AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2287162-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |
| EP-2284169-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders | Otsuka Pharmaceutical Co., Limited (JP) | 2011-02-16 | — | — | EP | disclosed |
| WO-2010097337-A1 | DRY COMPOSITION INCLUDING A BINDER AND A MODIFIED VEGETABLE OIL | SIKA TECHNOLOGY AG (CH) | 2010-09-02 | — | — | WO | disclosed |
| US-20090264404-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| EP-1048233-B1 | Shoe | ADIDAS INT MARKETING BV (NL) | 2006-04-26 | — | — | EP | disclosed |
| EP-1197157-B1 | Shoe | ADIDAS INT MARKETING BV (NL) | 2004-09-22 | — | — | EP | disclosed |
| EP-1197157-A1 | Shoe | adidas International B.V. (NL) | 2002-04-17 | — | — | EP | disclosed |
| EP-1048233-A2 | Shoe | adidas International B.V. (NL) | 2000-11-02 | — | — | EP | disclosed |