SCHEMBL132931

SCHEMBL132931

Cc1cccc(OP(=O)(Oc2cccc(C)c2C)N2CCN(P(=O)(Oc3cccc(C)c3C)Oc3cccc(C)c3C)CC2)c1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ GAA P10253 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ USP2 O75604 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ NR4A1 P22736 1/20 0.39
▸ CTSV O60911 2/20 0.38
▸ CTSL P07711 2/20 0.38
▸ CTSB P07858 2/20 0.38
▸ CTSS P25774 2/20 0.38
▸ CTSK P43235 2/20 0.38
▸ CTSC P53634 2/20 0.38
▸ CTSF Q9UBX1 2/20 0.38
▸ CTSH P09668 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130226 0.86 MAPT (0.45) MAPTNPSR1KMT2AMEN1GAA
SCHEMBL4827171 0.80 MAPT (0.40) MAPTNPSR1KMT2AMEN1GAA
SCHEMBL108985 0.77 MAPT (0.71) MAPTKMT2AMEN1GAALMNA
SCHEMBL4451361 0.76 MAPT (0.69) MAPTKMT2AMEN1GAALMNA
SCHEMBL497309 0.74 MAPT (0.67) MAPTKMT2AMEN1GAALMNA
SCHEMBL5667319 0.74 MAPT (0.67) MAPTKMT2AMEN1GAALMNA
SCHEMBL29429257 0.74 MAPT (0.67) MAPTGAALMNAMAPK1HTT
SCHEMBL30638309 0.74 MAPT (0.67) MAPTKMT2AMEN1GAALMNA
SCHEMBL759513 0.74 MAPT (0.67) MAPTGAALMNAMAPK1HTT
SCHEMBL9058483 0.74 MAPT (0.67) MAPTKMT2AMEN1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1452567-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-03-07 — — EP disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 — — EP disclosed
US-7411013-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2008-08-12 — — US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 — — US disclosed
US-7115677-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-10-03 — — US disclosed
US-20060074154-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-04-06 — — US disclosed
US-20040266916-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-30 — — US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 — — US disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 — — EP disclosed
EP-1452567-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-09-01 — — EP disclosed
Send feedback