Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 6/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132931 | 0.80 | MAPT (0.59) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL130226 | 0.79 | MAPT (0.45) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL940949 | 0.74 | MAPT (0.45) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL14204629 | 0.73 | LMNA (0.44) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL19084451 | 0.72 | SCN4A (0.41) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3757859 | 0.71 | MAPT (0.42) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL1486673 | 0.71 | MAPT (0.42) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL28397604 | 0.71 | MAPT (0.42) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL272850 | 0.71 | INPPL1 (0.43) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL2220467 | 0.71 | INPPL1 (0.59) | MAPTALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259519-B1 | METHOD FOR PREPARING STERICALLY HINDERED PHOSPHORAMIDATES | GEN ELECTRIC (US) | 2003-12-17 | — | — | EP | claimed |
| JP-2003524014-A | — | — | 2003-08-12 | — | — | JP | claimed |
| JP-2003508404-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1259519-A1 | METHOD FOR PREPARING STERICALLY HINDERED PHOSPHORAMIDATES | GENERAL ELECTRIC COMPANY (US) | 2002-11-27 | — | — | EP | claimed |
| WO-2001062766-A1 | METHOD FOR PREPARING STERICALLY HINDERED PHOSPHORAMIDATES | GENERAL ELECTRIC COMPANY (US) | 2001-08-30 | — | — | WO | claimed |
| US-6277988-B1 | REACTING STERICALLY HINDERED DIARYL CHLOROPHOSPHATE WITH A BASIC NITROGEN COMPOUND CONTAINING TWO SECONDARY AMINE GROUPS IN LIQUID SOLVENT-FREE REACTION MIXTURE TO FORM PHOSPHORAMIDATE AND HYDROGEN CHLORIDE BY-PRODUCT | GENERAL ELECTRIC COMPANY | 2001-08-21 | — | — | US | claimed |
| WO-2001016143-A1 | SOLVENT-FREE METHOD FOR PREPARING STERICALLY HINDERED PHOSPHORAMIDATES | GENERAL ELECTRIC COMPANY (US) | 2001-03-08 | — | — | WO | claimed |
| US-9884961-B2 | Phosphazene flame retardant polycarbonate compounds | POLYONE CORPORATION (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884961-B2 | Phosphazene flame retardant polycarbonate compounds | POLYONE CORPORATION (US) | 2018-02-06 | — | — | US | disclosed |
| US-20160272812-A1 | PHOSPHAZENE FLAME RETARDANT POLYCARBONATE COMPOUNDS | POLYONE CORPORATION (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272812-A1 | PHOSPHAZENE FLAME RETARDANT POLYCARBONATE COMPOUNDS | POLYONE CORPORATION (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160122534-A1 | COMPLETELY NON-HALOGENATED FLAME RETARDANT POLYCARBONATE COMPOUNDS | POLYONE CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160122534-A1 | COMPLETELY NON-HALOGENATED FLAME RETARDANT POLYCARBONATE COMPOUNDS | POLYONE CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
| WO-2001016143-A1 | SOLVENT-FREE METHOD FOR PREPARING STERICALLY HINDERED PHOSPHORAMIDATES | GENERAL ELECTRIC COMPANY (US) | 2001-03-08 | — | — | WO | disclosed |
| US-6191276-B1 | SUCH AS N,N'-BIS(DI-(2,6-XYLYL)PHOSPHORYL)PIPERAZINE, BY CONTACTING DI-(2,6-XYLYL) CHLOROPHOSPHATE WITH PIPERAZINE IN THE PRESENCE OF CALCIUM OXIDE AS ACID ACCEPTOR IN A DIPOLAR APORTIC SOLVENT; HIGH YIELD; USE AS FLAME RETARDANTS | GENERAL ELECTRIC COMPANY | 2001-02-20 | — | — | US | disclosed |
| US-6191276-B1 | SUCH AS N,N'-BIS(DI-(2,6-XYLYL)PHOSPHORYL)PIPERAZINE, BY CONTACTING DI-(2,6-XYLYL) CHLOROPHOSPHATE WITH PIPERAZINE IN THE PRESENCE OF CALCIUM OXIDE AS ACID ACCEPTOR IN A DIPOLAR APORTIC SOLVENT; HIGH YIELD; USE AS FLAME RETARDANTS | GENERAL ELECTRIC COMPANY | 2001-02-20 | — | — | US | disclosed |
| US-6166115-A | Flame resistant polyphenylene ether-polyamide resin blends | GENERAL ELECTRIC COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000012610-A1 | FLAME RESISTANT POLYPHENYLENE ETHER-POLYAMIDE RESIN BLENDS | GENERAL ELECTRIC COMPANY (US) | 2000-03-09 | — | — | WO | disclosed |
| US-5973041-A | THEMROPLASTIC RESIN BLENDED WITH AN AROMATIC BISPHOSPHORAMIDATE OF GIVNE FORMULA HAVING ACCEPTABLE FIRE RETARDING PROPERTIES AND A HIGHER HEAT DEFLECTION TEMPERTURE | GENERAL ELECTRIC COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| US-5973041-A | THEMROPLASTIC RESIN BLENDED WITH AN AROMATIC BISPHOSPHORAMIDATE OF GIVNE FORMULA HAVING ACCEPTABLE FIRE RETARDING PROPERTIES AND A HIGHER HEAT DEFLECTION TEMPERTURE | GENERAL ELECTRIC COMPANY (US) | 1999-10-26 | — | — | US | disclosed |