Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 8/20 | 0.35 |
| ▸ | FAAH | O00519 | 8/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10442245 | 0.74 | KDM4E (0.50) | KDM4ENAAAFAAH | |
| SCHEMBL8592112 | 0.73 | KDM4E (0.49) | KDM4ENAAAFAAH | |
| SCHEMBL15792768 | 0.72 | KDM4E (0.55) | KDM4ENAAAFAAHHSD11B1IDH1 | |
| SCHEMBL8151147 | 0.72 | KDM4E (0.48) | KDM4ENAAAFAAH | |
| Hydrochloric Acid SCHEMBL8591196 | 0.72 | KDM4E (0.48) | KDM4ENAAAFAAH | |
| SCHEMBL30252357 | 0.72 | KDM4E (0.48) | KDM4ENAAAFAAH | |
| SCHEMBL6820802 | 0.72 | KDM4E (0.51) | KDM4ENAAAFAAH | |
| SCHEMBL1516145 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL12068487 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL9575065 | 0.71 | KDM4E (0.47) | KDM4ENAAAFAAHHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065668-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |