SCHEMBL13295014

SCHEMBL13295014

Cc1cc(N(c2ccccc2)c2ccc(-n3c4ccccc4c4ccccc43)cc2)c(C)cc1-c1c2ccccc2c(-c2cc(C)c(N(c3ccccc3)c3ccc(-n4c5ccccc5c5ccccc54)cc3)cc2C)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
APP P05067 1/20 0.33
MAPK8 P45983 1/20 0.32
RORC P51449 1/20 0.31
PGR P06401 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
PLA2G2A P14555 1/20 0.30
PTPN1 P18031 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12893514 0.95 KDM4E (0.38) KDM4EATML3MBTL1APP
SCHEMBL13295013 0.93 KDM4E (0.36) KDM4EATML3MBTL1APP
SCHEMBL14362650 0.93 KDM4E (0.41) KDM4EATML3MBTL1MAPK8PGR
SCHEMBL12893516 0.89 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL12893518 0.89 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL14521274 0.89 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL13620153 0.89 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL13620152 0.89 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL13620150 0.88 KDM4E (0.40) KDM4EATML3MBTL1APPMAPK8
SCHEMBL14362565 0.87 KDM4E (0.36) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732064-B2 Anthracene derivative, and light-emitting element, light-emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-7732064-B2 Anthracene derivative, and light-emitting element, light-emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-20080114178-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-15 US disclosed
US-20080114178-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080114178-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same AFF1, NOX1, RER1 KDM4E 509/4885ATM 520/4885L3MBTL1 1878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.