RER1

Protein RER1 · O15258 · RER1 on Sugi Atlas →

208 patent compounds predicted against RER1, 195 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4699731 SCHEMBL4699731 1.00 2/20
SCHEMBL16111548 SCHEMBL16111548 1.00 2/20
SCHEMBL29358745 SCHEMBL29358745 1.00 2/20
SCHEMBL29380618 SCHEMBL29380618 1.00 2/20
SCHEMBL29931136 SCHEMBL29931136 1.00 2/20
SCHEMBL4697866 SCHEMBL4697866 0.89 2/20
SCHEMBL24532075 SCHEMBL24532075 0.89 2/20
SCHEMBL4697696 SCHEMBL4697696 0.86 2/20
SCHEMBL23092285 SCHEMBL23092285 0.86 2/20
SCHEMBL29688472 SCHEMBL29688472 0.86 2/20
SCHEMBL22024695 SCHEMBL22024695 0.86 2/20
SCHEMBL16136600 SCHEMBL16136600 0.84 2/20
SCHEMBL24532058 SCHEMBL24532058 0.83 2/20
SCHEMBL22025026 SCHEMBL22025026 0.82 2/20
SCHEMBL22119546 SCHEMBL22119546 0.82 2/20
SCHEMBL24532062 SCHEMBL24532062 0.82 2/20
SCHEMBL18804561 SCHEMBL18804561 0.81 2/20
SCHEMBL22024561 SCHEMBL22024561 0.81 2/20
SCHEMBL22025030 SCHEMBL22025030 0.81 2/20
SCHEMBL24532038 SCHEMBL24532038 0.81 2/20

Clinical trials — most relevant to RER1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis PHASE4COMPLETED
Betaine and Peroxisome Biogenesis Disorders PHASE3COMPLETED
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer PHASE2UNKNOWN
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Novel Peptide Vaccination for Patients With Advanced Bladder Cancer PHASE1COMPLETED
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations EARLY_PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Genetics of Rolandic Epilepsy nanCOMPLETED
Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions nanUNKNOWN
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study nanUNKNOWN
Neurogenetics Patient Registry nanRECRUITING
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate nanRECRUITING
Genetic and Functional Analysis of Aplasia Cutis Congenital (ACC) nanRECRUITING
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes nanRECRUITING
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING
Sodium Transport: Genetics and Hypertension nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders nanRECRUITING
Rolandic Epilepsy Genomewide Association International Study nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RER1 binder may also engage these)

ProteinNameSimilarity
Q9CQU3 1.000 Q9CQU3 →
Q5R5U4 1.000 Q5R5U4 →
A5PJ65 1.000 A5PJ65 →
Q498C8 1.000 Q498C8 →
Q5ZHM5 1.000 Q5ZHM5 →
Q1KZ54 1.000 Q1KZ54 →
P52879 1.000 P52879 →
O48670 0.999 O48670 →
P04124 0.998 P04124 →
Q77ZL5 0.998 Q77ZL5 →
Q77ZK8 0.998 Q77ZK8 →
Q1KXU2 0.998 Q1KXU2 →
P05779 0.997 P05779 →
Q67205 0.997 Q67205 →
Q77MS4 0.997 Q77MS4 →
P18033 0.997 P18033 →
P34395 0.997 P34395 →
Q6XT33 0.997 Q6XT33 →
P0DOF8 0.997 P0DOF8 →
P0DOF5 0.997 P0DOF5 →
A8C8W4 0.996 A8C8W4 →
Q1XD96 0.996 Q1XD96 →
P51391 0.996 P51391 →
P75083 0.996 P75083 →
P84392 0.996 P84392 →
Q10358 0.996 Q10358 →
P02657 0.996 P02657 →
Q76V12 0.996 Q76V12 →
Q89687 0.996 Q89687 →
Q7V4Q2 0.996 Q7V4Q2 →