Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13295235 | 0.83 | FAAH (0.42) | GRIN2BFAAHTRPV1NPC1 | |
| SCHEMBL3275071 | 0.82 | FAAH (0.57) | FAAHHTR2CHTR2ATRPV1NPC1 | |
| SCHEMBL13295167 | 0.82 | FAAH (0.56) | GRIN2BFAAHHTR2CHTR2ATRPV1 | |
| SCHEMBL13295164 | 0.82 | FAAH (0.52) | GRIN2BFAAHHTR2CHTR2ATRPV1 | |
| SCHEMBL13294922 | 0.82 | FAAH (0.49) | FAAH | |
| SCHEMBL3766417 | 0.79 | FAAH (0.61) | GRIN2BFAAHTRPV1NPC1RAB9A | |
| SCHEMBL3274877 | 0.77 | FAAH (0.58) | FAAHHTR2CHTR2ATRPV1POLB | |
| SCHEMBL13295175 | 0.75 | FAAH (0.49) | GRIN2BFAAHHTR2CHTR2ATRPV1 | |
| SCHEMBL32668648 | 0.75 | GRIN2B (0.55) | GRIN2BFAAHHTR2CTRPV1POLB | |
| SCHEMBL3274325 | 0.74 | FAAH (0.54) | GRIN2BFAAHTRPV1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064597-A1 | PIPERIDINE DERIVATIVE | 武田薬品工業株式会社 (JP) | 2010-06-10 | — | — | WO | disclosed |