Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 12/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27027024 | 0.88 | SLC29A1 (0.54) | SLC29A1CYP1A2CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL1032559 | 0.87 | SLC29A1 (0.49) | SLC29A1KMT2AGAAMEN1MAPK1 | |
| SCHEMBL13295561 | 0.85 | GAA (0.53) | SLC29A1CYP1A2CYP2C19KMT2AGAA | |
| SCHEMBL16374945 | 0.85 | SLC29A1 (0.50) | SLC29A1 | |
| SCHEMBL17817154 | 0.83 | SLC29A1 (0.67) | SLC29A1KMT2A | |
| SCHEMBL2219150 | 0.83 | SLC29A1 (0.49) | SLC29A1KMT2AGAAMEN1MAPK1 | |
| SCHEMBL15836258 | 0.82 | SLC29A1 (0.45) | SLC29A1CYP1A2CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL1691726 | 0.82 | SLC29A1 (0.51) | SLC29A1KMT2ASMN1; SMN2GAAMEN1 | |
| SCHEMBL16094288 | 0.81 | SLC29A1 (0.72) | SLC29A1CYP2C19KMT2ASMN1; SMN2GAA | |
| SCHEMBL3301414 | 0.80 | SLC29A1 (0.51) | SLC29A1KMT2ASMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736631-B2 | Cosmetic dye composition with a lightening effect for human keratin materials, comprising at least one fluorescent dye and at least one aminosilicone, and process of dyeing | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | disclosed |
| US-7736631-B2 | Cosmetic dye composition with a lightening effect for human keratin materials, comprising at least one fluorescent dye and at least one aminosilicone, and process of dyeing | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | disclosed |
| US-20090288674-A1 | COSMETIC DYE COMPOSITION WITH A LIGHTENING EFFECT FOR HUMAN KERATIN MATERIALS, COMPRISING AT LEAST ONE FLUORESCENT DYE AND AT LEAST ONE AMINOSILICONE, AND PROCESS OF DYEING | L'OREAL S.A. | 2009-11-26 | — | — | US | disclosed |
| US-20090288674-A1 | COSMETIC DYE COMPOSITION WITH A LIGHTENING EFFECT FOR HUMAN KERATIN MATERIALS, COMPRISING AT LEAST ONE FLUORESCENT DYE AND AT LEAST ONE AMINOSILICONE, AND PROCESS OF DYEING | L'OREAL S.A. | 2009-11-26 | — | — | US | disclosed |
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | disclosed |
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | disclosed |
| US-7303589-B2 | Process for dyeing human keratin fibers, having a lightening effect, comprising at least one fluorescent compound and compositions of the same | L'OREAL S.A. (FR) | 2007-12-04 | — | — | US | disclosed |
| US-7250064-B2 | Dye composition comprising at least one fluorescent dye and a non-associative thickening polymer for human keratin materials, process therefor, and method thereof | L'OREAL S.A. (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7208018-B2 | Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one associative polymer, process therefor and use thereof | L'OREAL (FR) | 2007-04-24 | — | — | US | disclosed |
| US-7204860-B2 | Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one polyol, process therefor and use thereof | L'OREAL (FR) | 2007-04-17 | — | — | US | disclosed |
| US-7198650-B2 | Method of dyeing human keratin materials with a lightening effect with compositions comprising at least one fluorescent dye and at least one amphoteric or nonionic surfactant, composition thereof, process thereof, and device therefor | L'OREAL S.A. (FR) | 2007-04-03 | — | — | US | disclosed |
| US-7195651-B2 | Cosmetic composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one cationic polymer, and a dyeing process therefor | L'OREAL S.A. (FR) | 2007-03-27 | — | — | US | disclosed |
| US-7195650-B2 | Process for dyeing, with a lightening effect, human keratin fibers that have been permanently reshaped, using at least one composition comprising at least one fluorescent dye | L'OREAL S.A. (FR) | 2007-03-27 | — | — | US | disclosed |
| US-7192454-B2 | Composition for dyeing human keratin materials, comprising a fluorescent dye and a particular sequestering agent, process therefor and use thereof | L'OREAL S.A. (FR) | 2007-03-20 | — | — | US | disclosed |
| US-7186278-B2 | Composition for dyeing human keratin materials, comprising at least one fluorescent dye and at least one compound comprising an acid functional group and processes therefor | L'OREAL S.A. (FR) | 2007-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | KRT18, VIM, CD44 | SLC29A1 4846/4885CYP1A2 2856/4885CYP2C19 1990/4885 |
| US-20090288674-A1 | COSMETIC DYE COMPOSITION WITH A LIGHTENING EFFECT FOR HUMAN KERATIN MATERIALS, COMPRISING AT LEAST ONE FLUORESCENT DYE AND AT LEAST ONE AMINOSILICONE, AND PROCESS OF DYEING | KRT18, MARK1, CUTA | SLC29A1 4486/4885CYP1A2 3350/4885CYP2C19 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.