Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5297053 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL21051537 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL12869205 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL15014467 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL21872285 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL3053628 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL10147187 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL9810706 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL26027171 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL12424656 | 0.71 | ALDH1A1 (0.59) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732416-B2 | For protecting plants against parasitic feeding pests; also against the infestation of pets, especially cats and dogs, by fleas, ticks and nematodes; pesticides for crop protection | MERIAL LIMITED (US) | 2010-06-08 | — | — | US | disclosed |
| US-7605134-B2 | Pesticides | MERIAL LIMITED (US) | 2009-10-20 | — | — | US | disclosed |
| EP-1421094-B1 | 4\"-DEOXY-4\"-(S)-AMINO AVERMECTIN DERIVATIVES | MERIAL LTD (GB) | 2008-10-15 | — | — | EP | disclosed |