Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL2650732 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL28409881 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL29197512 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL1716773 | 1.00 | — | — | |
| Butane SCHEMBL21633593 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL1165212 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL28896048 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL40275 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL4012929 | 0.95 | FFAR3 (0.50) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL9235538 | 0.95 | FFAR3 (0.50) | FFAR3HDAC1HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10087399-B2 | Use of alkoxylated non-ionic surfactants as additive in aqueous membrane cleaning compositions | BASF SE (DE) | 2018-10-02 | — | — | US | disclosed |
| EP-2776548-B1 | EMULSIONS CONTAINING POLYMERIC CATIONIC EMULSIFIERS, SUBSTANCE AND PROCESS | BASF SE (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-2872609-B1 | USE OF ALKOXYLATED NON-IONIC SURFACTANTS AS ADDITIVE IN AQUEOUS MEMBRANE CLEANING COMPOSITIONS | BASF SE (DE) | 2018-02-14 | — | — | EP | disclosed |
| EP-2569370-B1 | EMULSIONS OF POLYISOBUTENES, SUBSTANCE AND PROCESS | BASF SE (DE) | 2016-08-24 | — | — | EP | disclosed |
| US-20150175936-A1 | USE OF ALKOXYLATED NON-IONIC SURFACTANTS AS ADDITIVE IN AQUEOUS MEMBRANE CLEANING COMPOSITIONS | BASF SE (DE) | 2015-06-25 | — | — | US | disclosed |
| EP-2776149-A2 | EMULSIONS CONTAINING POLYMERIC CATIONIC EMULSIFIERS, SUBSTANCE AND PROCESS | BASF SE (DE) | 2014-09-17 | — | — | EP | disclosed |
| EP-2776548-A1 | EMULSIONS CONTAINING POLYMERIC CATIONIC EMULSIFIERS, SUBSTANCE AND PROCESS | The Procter and Gamble Company (US) | 2014-09-17 | — | — | EP | disclosed |
| US-8759274-B2 | Self-emulsifiable polyolefine compositions | BASF SE (DE) | 2014-06-24 | — | — | US | disclosed |
| US-8536108-B2 | Care polymers | THE PROCTER & GAMBLE COMPANY (US) | 2013-09-17 | — | — | US | disclosed |
| US-20130123160-A1 | SELF-EMULSIFIABLE POLYOLEFINE COMPOSITIONS | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| EP-2128144-A1 | Amphiphilic molecules with a triazine core | BASF SE (DE) | 2009-12-02 | — | — | EP | disclosed |
| EP-2128143-A1 | Amphiphilic molecules with a triazine core | BASF SE (DE) | 2009-12-02 | — | — | EP | disclosed |
| EP-2128142-A1 | Amphiphilic molecules with a triazine core | BASF SE (DE) | 2009-12-02 | — | — | EP | disclosed |
| US-7612455-B2 | Layered structure for electron device including regions of different wettability, electron device and electron device array that uses such a layered structure | RICOH COMPANY, LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| EP-1885787-A1 | PHOSPHITE ADDITIVES IN POLYOLEFINS | Philips Petroleum Company (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006124018-A1 | PHOSPHITE ADDITIVES IN POLYOLEFINS | PHILLIPS PETROLEUM COMPANY (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20040238816-A1 | Layered structure and electron device that uses such a layered structure, fabrication process thereof, electron device array and dispaly apparatus | RICOH COMPANY, LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-0556559-B1 | Method for producing heat resistant coatings upon wires or fibres and device suitable for performing it | HERBERTS & CO GMBH (DE) | 1997-09-17 | — | — | EP | disclosed |
| EP-0556559-A1 | Method for producing heat resistant coatings upon wires or fibres and device suitable for performing it | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1993-08-25 | — | — | EP | disclosed |
| US-3947384-A | EPOXY COMPOUND, POLYCARBOXYLIC ACID AND CYCLIC AMIDINE | VEBA-CHEMIE AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | disclosed |