Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL1329645 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL2650732 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL28409881 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL29197512 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL1716773 | 1.00 | — | — | |
| Butane SCHEMBL21633593 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL1165212 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL28896048 | 1.00 | FFAR3 (0.54) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL4012929 | 0.95 | FFAR3 (0.50) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL9235538 | 0.95 | FFAR3 (0.50) | FFAR3HDAC1HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5138 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707895-A | Preparation method of 7-formyl-2, 3-dihydrobenzofuran-4-carbonitrile | 江苏苏中药业研究院有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-114907241-B | Guanidine compound containing fluorosulfonyl group, and preparation method and application thereof | 中宏鑫投资控股(深圳)有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117756882-A | Preparation method of L-glutamyl-L-alanine | 武汉桀升生物科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2024034746-A1 | METHOD FOR PRODUCING ASYMMETRIC RING-OPENING REACTION PRODUCT OF CYCLIC ANHYDRIDE USING ORGANIC CHIRAL CATALYST COMPOUNDS | 고려대학교 산학협력단 | 2024-02-15 | — | — | WO | claimed |
| CN-117417272-A | Preparation method of Boc-D-isoleucine | 上海海皋科技有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-117024379-B | Preparation method and application of 2-amino-4- (4-methyl-1-piperazine) benzoic acid tert-butyl ester | 济南国鼎医药科技有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117024379-A | Preparation method and application of 2-amino-4- (4-methyl-1-piperazine) benzoic acid tert-butyl ester | 济南国鼎医药科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116556107-A | Protective liquid for protecting paper cultural relics | 郑州大学 | 2023-08-08 | — | — | CN | claimed |
| CN-115057803-A | S- (methyl-d) 3 ) Synthetic method and application of phenylether substances | 杭州师范大学 | 2022-09-16 | — | — | CN | claimed |
| CN-214634114-U | Di-tert-butyl dicarbonate rectifying device for recovering crystallization mother liquor | 杭州凯名庞德生物科技有限公司 | 2021-11-09 | — | — | CN | claimed |
| US-5658435-A | USING AZEOTROPE FORMING AGENT SUCH AS SULFOLANE | BERG LLOYD (US) | 1997-08-19 | — | — | US | claimed |
| EP-0784621-A1 | QUINIDINE CONJUGATES AND THEIR USE IN IMMUNOASSAYS | Dade Chemistry Systems Inc. (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0767819-A1 | pH-MODIFIED BIOCOMPATIBLE MONOMER AND POLYMER COMPOSITIONS | TRI-POINT MEDICAL CORPORATION (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1997006166-A1 | QUINIDINE CONJUGATES AND THEIR USE IN IMMUNOASSAYS | DADE CHEMISTRY SYSTEMS INC. (US) | 1997-02-20 | — | — | WO | claimed |
| WO-1996000760-A1 | pH-MODIFIED BIOCOMPATIBLE MONOMER AND POLYMER COMPOSITIONS | TRI-POINT MEDICAL CORPORATION (US) | 1996-01-11 | — | — | WO | claimed |
| EP-0591333-A1 | AZANORBORNANE DERIVATIVES. | PFIZER (US) | 1994-04-13 | — | — | EP | claimed |
| EP-0574135-A1 | Process for producing peptide derivatives and salts thereof | JAPAN ENERGY CORPORATION (JP) | 1993-12-15 | — | — | EP | claimed |
| US-5194629-A | PROCESS FOR PRODUCING N-TERTIARY BUTOXYCARBONYL-MALEINIMIDE | SIEMENS AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | claimed |
| US-5188682-A | PROPELLENT MEDIUM FOR HYBRID WEAPON | DIEHL GMBH & CO. (DE) | 1993-02-23 | — | — | US | claimed |
| WO-1993000330-A2 | AZANORBORNANE DERIVATIVES | PFIZER INC. (US) | 1993-01-07 | — | — | WO | claimed |