Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12736416 | 0.94 | HTT (0.50) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL10138722 | 0.91 | SMN1; SMN2 (0.47) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL12736446 | 0.90 | SMN1; SMN2 (0.44) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL12276812 | 0.90 | TSHR (0.54) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL24977924 | 0.89 | SMN1; SMN2 (0.45) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL17169232 | 0.88 | HTT (0.50) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL20370948 | 0.87 | PKM (0.46) | TSHRGAASMN1; SMN2HTTNR1I2 | |
| SCHEMBL17172538 | 0.85 | POLB (0.44) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL13297310 | 0.84 | GSK3B (0.48) | TSHRPOLBMAPK1GAASMN1; SMN2 | |
| SCHEMBL17169295 | 0.83 | HTT (0.54) | TSHRPOLBMAPK1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736539-B2 | Ion-conducting polymers and membranes comprising them | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2010-06-15 | — | — | US | disclosed |
| EP-1704175-B1 | ION-CONDUCTING POLYMERS AND MEMBRANES COMPRISING THEM | JOHNSON MATTHEY PLC (GB) | 2008-10-15 | — | — | EP | disclosed |
| US-20070196734-A1 | Ion-Conducting Polymers And Membranes Comprising Them | Johnson Matthey Hydrogen Technologies Limited (GB) | 2007-08-23 | — | — | US | disclosed |