Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13297742 | 0.95 | CYP19A1 (0.77) | CYP19A1 | |
| SCHEMBL13297744 | 0.92 | CYP19A1 (0.72) | CYP19A1 | |
| SCHEMBL13297756 | 0.92 | CYP19A1 (0.77) | CYP19A1 | |
| SCHEMBL13297755 | 0.91 | CYP19A1 (0.72) | CYP19A1 | |
| SCHEMBL13297747 | 0.91 | CYP19A1 (0.72) | CYP19A1 | |
| SCHEMBL13297743 | 0.90 | CYP19A1 (0.73) | CYP19A1 | |
| SCHEMBL13297766 | 0.89 | CYP19A1 (0.66) | CYP19A1 | |
| SCHEMBL13297748 | 0.89 | CYP19A1 (0.66) | CYP19A1 | |
| SCHEMBL13297750 | 0.88 | CYP19A1 (0.73) | CYP19A1 | |
| SCHEMBL13297740 | 0.84 | CYP19A1 (0.74) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741520-B2 | Sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-06-22 | — | — | US | disclosed |
| US-7741520-B2 | Sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-06-22 | — | — | US | disclosed |
| US-20080045598-A1 | Novel sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY (US) | 2008-02-21 | — | — | US | disclosed |
| US-20080045598-A1 | Novel sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY (US) | 2008-02-21 | — | — | US | disclosed |
| WO-2007120379-A2 | SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045598-A1 | Novel sulfonanilide analogs as selective aromatase modulators (SAMs) | CYP19A1, AR, SULT2A1 | CYP19A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.