SULT2A1

Sulfotransferase 2A1 · Q06520 · SULT2A1 on Sugi Atlas →

214 patent compounds predicted against SULT2A1, 193 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL9904844 SCHEMBL9904844 1.00 1/20
SCHEMBL9904845 SCHEMBL9904845 1.00 1/20
SCHEMBL11919898 SCHEMBL11919898 1.00 1/20
SCHEMBL29372843 SCHEMBL29372843 1.00 1/20
SCHEMBL35212190 SCHEMBL35212190 1.00 1/20
SCHEMBL9905154 SCHEMBL9905154 0.86 1/20
SCHEMBL9905155 SCHEMBL9905155 0.86 1/20
SCHEMBL11919903 SCHEMBL11919903 0.86 1/20
SCHEMBL23772382 SCHEMBL23772382 0.86 1/20
SCHEMBL16010756 SCHEMBL16010756 0.86 1/20
SCHEMBL9926244 SCHEMBL9926244 0.85 1/20
SCHEMBL15449894 SCHEMBL15449894 0.84 1/20
SCHEMBL11919900 SCHEMBL11919900 0.83 1/20
SCHEMBL9926210 SCHEMBL9926210 0.81 1/20
SCHEMBL11919901 SCHEMBL11919901 0.80 1/20
SCHEMBL13046998 SCHEMBL13046998 0.80 1/20
SCHEMBL15449865 SCHEMBL15449865 0.79 1/20
SCHEMBL11919979 SCHEMBL11919979 0.77 1/20
SCHEMBL15449805 SCHEMBL15449805 0.75 1/20
SCHEMBL11919910 SCHEMBL11919910 0.75 1/20

Clinical trials — most relevant to SULT2A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity PHASE4COMPLETED
Comparison of Two Different Doses of Paracetamol for Post-Operative Pain Relief PHASE4COMPLETED
Pharmacogenetics of Nicotine Addiction Treatment PHASE3COMPLETED
Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer PHASE2COMPLETED
Activity of Regorafenib in Combination With Chemotherapy in Patients With Advanced Biliary Tract Cancer PHASE1/PHASE2COMPLETED
Variability of Sulfotransferase 1A1 Activity in Humans: an Approach to Improve Predictive Drug Response - Part I: Analysis of Intraindividual Variation in Healthy Adults PHASE1COMPLETED
Variability of Sulfotransferase Activity in Humans: an Approach to Improve Predictive Drug Response Part II: Analysis of Interindividual Variation in Hypertensive Patients PHASE1COMPLETED
2-Methoxyestradiol in Treating Patients With Advanced Solid Tumors PHASE1COMPLETED
Pharmacokinetics, Metabolism and Analgesic Effects of Flupirtine PHASE1COMPLETED
Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects PHASE1COMPLETED
Atazanavir/Ritonavir and Darunavir/Ritonavir PK Tail Study PHASE1COMPLETED
Bioavailability of Paracetamol, Amoxicillin and Talinolol Before, Immediately and One Year After Gastric Bypass Operation PHASE1COMPLETED
PK of Tenofovir, Emtricitabine and Efavirenz in Healthy Volunteers PHASE1COMPLETED
Pharmacokinetics (PK) Study of Once Daily Darunavir/Ritonavir and Twice and Once Daily Raltegravir in HIV-infected Subjects PHASE1COMPLETED
Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet EARLY_PHASE1COMPLETED
Contribution of UGT2B17 to the Pharmacokinetics of Diclofenac EARLY_PHASE1RECRUITING
Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline nanCOMPLETED
APAP Hepatotoxicity After Therapeutic Doses nanUNKNOWN
Genetic Polymorphisms in UGT1A6 and UGT2B7 in Asian Population: Association With Lung Cancer Phenotype nanUNKNOWN
The Clinical and Economic Impact of Pharmacogenomic Testing for Tamoxifen Metabolism in Postmenopausal Women Receiving Tamoxifen for Prevention of Recurrent Breast Cancer nanCOMPLETED
A Pilot Study of Varying Doses of Tamoxifen in the Setting of Genetic Polymorphisms of CYP2D6 nanCOMPLETED
Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant nanRECRUITING
Aromatase Inhibitor Clinical Trial nanUNKNOWN
Measurement of Risperidone and 9-Hydroxyrisperidone in Plasma and Saliva nanCOMPLETED
Studying Urine and Blood Samples in Women With Newly Diagnosed Breast Cancer nanCOMPLETED
Individualized Antiretroviral Therapy nanCOMPLETED
Pharmacogenetics of Anastrozole in Postmenopausal Women With Estrogen Receptor-Positive and/or Progesterone Receptor-Positive Stage I, Stage II, or Stage III Breast Cancer nanCOMPLETED
Effects of Genotype on CYP2C9 Drug Interactions nanCOMPLETED
Pharmacogenetic Determinants Of Treatment Response In Children nanRECRUITING
Genetic Study of Patients Previously Treated With Flavopiridol on Clinical Trial NCI-97-C-0171C nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SULT2A1 binder may also engage these)

ProteinNameSimilarity
P52841 1.000 P52841 →
P52842 1.000 P52842 →
B2RVI8 0.999 B2RVI8 →
P50236 0.997 P50236 →
P15709 0.995 P15709 →
P22789 0.994 P22789 →
P52843 0.993 P52843 →
P50234 0.992 P50234 →
P50235 0.991 P50235 →
Q29476 0.989 Q29476 →
P49887 0.989 P49887 →
P19217 0.989 P19217 →
Q9QWG7 0.989 Q9QWG7 →
Q8BGL3 0.988 Q8BGL3 →
Q6WG18 0.988 Q6WG18 →
O43704 0.988 O43704 →
P52840 0.988 P52840 →
G3V9R3 0.988 G3V9R3 →
Q3UZZ6 0.988 Q3UZZ6 →
P0DMM9 0.987 P0DMM9 →
P0CC03 0.987 P0CC03 →
Q9WUW9 0.986 Q9WUW9 →
P0DMN0 0.986 P0DMN0 →
A0A2K5X3B6 0.986 A0A2K5X3B6 →
SULT1A1 Sulfotransferase 1A1 0.986 landscape →
O00338 0.986 O00338 →
Q6IMI4 0.986 Q6IMI4 →
Q6PH37 0.985 Q6PH37 →
P50227 0.985 P50227 →
O46503 0.985 O46503 →