SCHEMBL132995

SCHEMBL132995

O=C(S)c1ccccc1-c1ncccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
HCRTR1 O43613 4/20 0.39
HCRTR2 O43614 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
KMT2A Q03164 2/20 0.39
CHRNB2 P17787 2/20 0.39
CHRNB4 P30926 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465563 0.82 KDM4E (0.55) KDM4ETDP1L3MBTL1KMT2AALDH1A1
SCHEMBL10383776 0.81 KDM4E (0.46) KDM4ETDP1HCRTR1HCRTR2L3MBTL1
SCHEMBL31227695 0.80 CSNK1A1 (0.57) KDM4EALDH1A1CYP3A4MAPTTSHR
SCHEMBL16025408 0.80 HCRTR1 (0.42) KDM4ETDP1HCRTR1HCRTR2L3MBTL1
SCHEMBL997870 0.80 CSNK1A1 (0.57) KDM4EALDH1A1CYP3A4MAPTTSHR
SCHEMBL17449218 0.80 KDM4C (0.57) KDM4ETDP1HCRTR1HCRTR2L3MBTL1
SCHEMBL17448835 0.77 HCRTR2 (0.43) KDM4EHCRTR1HCRTR2L3MBTL1KMT2A
SCHEMBL16856649 0.76 HCRTR1 (0.45) HCRTR1HCRTR2L3MBTL1KMT2AALDH1A1
SCHEMBL1586163 0.76 SLC6A3 (0.54) KDM4ETDP1L3MBTL1KMT2AALDH1A1
SCHEMBL19287257 0.76 PDK2 (0.42) KDM4ETDP1HCRTR1HCRTR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2072 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3664607-B1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND TEMBOTRIONE AND/OR TOPRAMEZONE CORTEVA AGRISCIENCE LLC (US) 2026-04-08 EP claimed
EP-3468366-B1 SAFENED HERBICIDAL COMPOSITIONS CONTAINING HALAUXIFEN AND METHODS OF USE THEREOF IN BRASSICA SPECIES CORTEVA AGRISCIENCE LLC (US) 2024-07-31 EP claimed
EP-4351321-A1 SESAME PLANTS RESISTANT TO ACETOLACTATE SYNTHASE-INHIBITING HERBICIDES, COMPOSITIONS AND METHODS FOR PRODUCING SAME Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2024-04-17 EP claimed
US-20240074371-A1 An embryo rescue and in vitro herbicidal selection method for sunflower SYNGENTA CROP PROTECTION AG (CH) 2024-03-07 US claimed
CN-117545346-A Sesame plants resistant to acetolactate synthase-inhibiting herbicides, compositions and methods of producing the same 耶路撒冷希伯来大学伊森姆研究发展有限公司 2024-02-09 CN claimed
EP-4277456-A2 AN EMBRYO RESCUE AND IN VITRO HERBICIDAL SELECTION METHOD FOR SUNFLOWER Syngenta Crop Protection AG (CH) 2023-11-22 EP claimed
US-20230257761-A1 HERBICIDE RESISTANT PLANT INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2023-08-17 US claimed
CN-113613495-B Compositions comprising clopyralid and other herbicides and methods thereof 美国陶氏益农公司 2023-05-23 CN claimed
CN-113271777-B Compositions comprising clopyralid and other herbicides and methods thereof 美国陶氏益农公司 2023-05-23 CN claimed
WO-2022259249-A1 SESAME PLANTS RESISTANT TO ACETOLACTATE SYNTHASE-INHIBITING HERBICIDES, COMPOSITIONS AND METHODS FOR PRODUCING SAME YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2022-12-15 WO claimed
EP-0953646-B1 Herbicide tolerant transgenic plants where the herbicide inhibits prophyrin biosynthesis SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP claimed
WO-2008150473-A2 CYTOCHROME P450 GENES CONFERRING HERBICIDE RESISTANCE SYNGENTA PARTICIPATIONS AG (CH) 2008-12-11 WO claimed
US-20080254983-A1 Herbicide Composition NUFARM AUSTRALIA LIMITED (AU) 2008-10-16 US claimed
US-20080216187-A1 Acetolactate Synthase Herbicide Resistant Sorghum KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2008-09-04 US claimed
EP-1933621-A1 HERBICIDE COMPOSITION NUFARM AUSTRALIA LIMITED (AU) 2008-06-25 EP claimed
WO-2008073800-A2 ACETOLACTATE SYNTHASE HERBICIDE RESISTANT SORGHUM KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2008-06-19 WO claimed
WO-2007030887-A1 HERBICIDE COMPOSITION NUFARM AUSTRALIA LIMITED (AU) 2007-03-22 WO claimed
WO-2006009964-A2 NOVEL ESTERS AS USEFUL HERBICIDAL COMPOUNDS CORET JOEL MARCEL (US) 2006-01-26 WO claimed
US-20050282708-A1 Novel esters as useful herbicidal compounds CORET JOEL M 2005-12-22 US claimed
EP-0953646-A2 Herbicide tolerant transgenic plants where the herbicide inhibits prophyrin biosynthesis SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-03 EP claimed