Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 12/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094503 | 0.90 | RBP4 (0.69) | RBP4MEN1KMT2APLA2G1BATG4B | |
| SCHEMBL3100376 | 0.89 | RBP4 (0.61) | RBP4MEN1KMT2ALMNAPOLB | |
| SCHEMBL18404361 | 0.89 | RBP4 (0.61) | RBP4MEN1KMT2ALMNAPOLB | |
| SCHEMBL3108139 | 0.89 | RBP4 (0.65) | RBP4MEN1KMT2APLA2G1BATG4B | |
| SCHEMBL3105986 | 0.87 | RBP4 (0.62) | RBP4MEN1KMT2ALMNAPOLB | |
| SCHEMBL13299516 | 0.86 | RBP4 (0.63) | RBP4 | |
| SCHEMBL3107777 | 0.86 | RBP4 (0.58) | RBP4MEN1KMT2ALMNAPOLB | |
| SCHEMBL15511167 | 0.85 | RBP4 (0.57) | RBP4MEN1KMT2APLA2G1BATG4B | |
| SCHEMBL3113132 | 0.85 | RBP4 (0.57) | RBP4 | |
| SCHEMBL18404037 | 0.84 | RBP4 (0.58) | RBP4NPSR1PLA2G1BATG4BRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202223-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-06-30 | — | — | EP | disclosed |