RBP4 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL631591	1.00	20/20
SCHEMBL613346	0.56	19/20
SCHEMBL766148	0.56	19/20
SCHEMBL613550	0.54	19/20
SCHEMBL630501	1.00	18/20
SCHEMBL631625	1.00	18/20
SCHEMBL630598	0.78	18/20
SCHEMBL766152	0.70	18/20
SCHEMBL766267	0.58	18/20
SCHEMBL614775	0.53	18/20
Hydrochloric Acid (SCHEMBL614973)	0.53	18/20
SCHEMBL615322	0.51	18/20
SCHEMBL614646	0.50	18/20
SCHEMBL766261	0.79	17/20
SCHEMBL631783	0.78	17/20
SCHEMBL630573	0.76	17/20
SCHEMBL766147	0.72	17/20
SCHEMBL766150	0.68	17/20
SCHEMBL632039	0.67	17/20
SCHEMBL766151	0.66	17/20

Clinical trials — most relevant to RBP4 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Impact of Omega-3 Supplementation on Gene Expression in Type 2 Diabetics	PHASE4	UNKNOWN
Vitamin D, K2 Plus Empagliflozin Combination in Type Two Diabetes Mellitus	PHASE3	UNKNOWN
Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19	PHASE2	UNKNOWN
Effect of Vitamin D Replacement on Insulin Sensitivity	PHASE1	COMPLETED
Retinol Binding Protein 4 Protein in Alopecia Areata Treated With Barcitinib	PHASE1	ACTIVE_NOT_RECRUITING
Fenretinide in Treating Children With Solid Tumors	PHASE1	COMPLETED
Effect of Short-Term Exercise Training on ATP Synthesis in Relatives of Type 2 Diabetic Humans	nan	COMPLETED
High/Low Dose Vit A in Diarrhea/ALRI in Severe PEM	nan	COMPLETED
Retinol-binding Protein 4 (RBP4) Metabolizm in Type 2 Diabetes Progression and Associated Cardiovascular Complications	nan	UNKNOWN
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective	nan	COMPLETED
The Effect of Whole Almonds on Biomarkers of Cardiovascular Disease in Chinese Patients With Type 2 Diabetes	nan	COMPLETED
Serum CTRP3 and RBP4 Levels in Obesity and Hypertension	nan	COMPLETED
Apelin12 in Acne Vulgaris	nan	UNKNOWN
Effects of Gender-Affirming Hormone Therapy on Cardiovascular, Metabolic, and Mental Health Outcomes in Transgender Adults.	nan	NOT_YET_RECRUITING
Fruit and Vegetable Juice Concentrate Effects on RBP4 and Antioxidant Capacity in Lean and Overweight 6-10 Year Old Boys	nan	COMPLETED
Total Body Vitamin A Before and After Vitamin A Supplementation in a Community Where Liver is Frequently Eaten	nan	COMPLETED
Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters.	nan	COMPLETED
Insulin Resistance And End Stage Renal Disease: The Role Of Retinol Binding Protein 4	nan	UNKNOWN
Using Stable Isotope Techniques to Monitor and Assess the Vitamin A Status of Children Susceptible to Infection	nan	COMPLETED
The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool Children	nan	COMPLETED
EVOO and Metabolic Liver Health in MASLD	nan	RECRUITING
Effects of Thyroid Hormone Withdrawal on Metabolic Parameters During Radioactive Iodine Therapy in Thyroid Cancer	nan	UNKNOWN
Vitamin A and D Intake in Pregnancy, Infant Supplementation and Asthma Development	nan	COMPLETED
Development of a Novel Biomarker for Liver Fibrosis	nan	COMPLETED
Biomedical Investigations for Optimized Diagnosis and Monitoring of Severe Acute Malnutrition (SAM): Elucidating the Heterogeneous Diagnosis of SAM by Current Anthropometric Criteria and Moving Beyond	nan	COMPLETED
Dynamic Parameters of Glucose Control in Relation to Biomarkers in Serum and Intraocular Fluid in Patients With Diabetes	nan	UNKNOWN
Validation and Simplification of the Retinol Isotope Dilution Technique in Burkinabe Schoolchildren	nan	RECRUITING
Prevalence Of Vitamin A Deficiency In Critically Ill Children With Sepsis And Its Association With Clinical Outcomes	nan	COMPLETED
Replacement of Vitamin D in Patients With Active Tuberculosis	nan	COMPLETED
Biomarkers In Retinitis Pigmentosa (BIRP)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RBP4 binder may also engage these)

Protein	Name	Similarity
P27485	—	1.000	P27485 →
P61641	—	1.000	P61641 →
M5AXY1	—	1.000	M5AXY1 →
Q00724	—	1.000	Q00724 →
P04916	—	1.000	P04916 →
Q28369	—	1.000	Q28369 →
P06912	—	0.998	P06912 →
P06172	—	0.998	P06172 →
P18902	—	0.995	P18902 →
P41263	—	0.995	P41263 →
P08938	—	0.995	P08938 →
P24774	—	0.990	P24774 →
P24775	—	0.986	P24775 →
Q86PT9	—	0.984	Q86PT9 →
P06910	—	0.982	P06910 →
P54962	—	0.982	P54962 →
P86785	—	0.981	P86785 →
Q5RB02	—	0.980	Q5RB02 →
Q94733	—	0.979	Q94733 →
Q26241	—	0.979	Q26241 →
Q08E66	—	0.979	Q08E66 →
B3A0S3	—	0.979	B3A0S3 →
P00305	—	0.978	P00305 →
CTSC	Dipeptidyl peptidase 1	0.978	landscape →
Q26239	—	0.978	Q26239 →
Q5ECE3	—	0.978	Q5ECE3 →
Q8TEU8	—	0.978	Q8TEU8 →
Q7TQN3	—	0.978	Q7TQN3 →
Q66H42	—	0.977	Q66H42 →
Q6PQK2	—	0.977	Q6PQK2 →