Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 12/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113543 | 0.88 | RBP4 (0.77) | RBP4CHRM3TTRALDH1A1KDM4E | |
| SCHEMBL3105846 | 0.86 | RBP4 (1.00) | RBP4ALDH1A1KDM4EGAA | |
| SCHEMBL3110525 | 0.86 | RBP4 (0.73) | RBP4TTRALDH1A1KDM4EGAA | |
| SCHEMBL18404251 | 0.86 | RBP4 (0.80) | RBP4TTRALDH1A1KDM4EGAA | |
| SCHEMBL3104804 | 0.85 | RBP4 (1.00) | RBP4TTRALDH1A1KDM4EGAA | |
| SCHEMBL3111960 | 0.84 | RBP4 (0.70) | RBP4TTRALDH1A1KDM4EGAA | |
| SCHEMBL3105695 | 0.83 | RBP4 (0.74) | RBP4TTRALDH1A1KDM4EGAA | |
| SCHEMBL18404238 | 0.83 | RBP4 (0.78) | RBP4TTRALDH1A1KDM4EGAA | |
| SCHEMBL3094577 | 0.83 | RBP4 (0.78) | RBP4ALDH1A1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18404500 | 0.83 | RBP4 (0.74) | RBP4TTRALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202223-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-06-30 | — | — | EP | disclosed |