⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17011754 | 0.82 | HDAC3 (0.46) | — | |
| SCHEMBL13301104 | 0.80 | — | — | |
| SCHEMBL17399724 | 0.79 | HDAC3 (0.54) | — | |
| SCHEMBL6636483 | 0.76 | MAPT (0.52) | — | |
| SCHEMBL17399723 | 0.76 | — | — | |
| SCHEMBL3895491 | 0.75 | — | — | |
| SCHEMBL14271512 | 0.75 | — | — | |
| SCHEMBL3538392 | 0.74 | — | — | |
| SCHEMBL10023005 | 0.73 | KDM4E (0.37) | — | |
| SCHEMBL13056338 | 0.73 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160195540-A1 | Molecular Conjugate | VENTANA MED SYST INC (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160195540-A1 | Molecular Conjugate | VENTANA MED SYST INC (US) | 2016-07-07 | — | — | US | disclosed |
| US-9310373-B2 | Molecular conjugate | VENTANA MEDICAL SYSTEMS, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-9310373-B2 | Molecular conjugate | VENTANA MEDICAL SYSTEMS, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| EP-2963011-A1 | MOLECULAR CONJUGATE | Ventana Medical Systems, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-1951316-B1 | Molecular conjugate | VENTANA MED SYST INC (US) | 2015-08-19 | — | — | EP | disclosed |
| US-20140205995-A1 | MOLECULAR CONJUGATE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140205995-A1 | MOLECULAR CONJUGATE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-07-24 | — | — | US | disclosed |
| US-20100136652-A1 | Molecular Conjugate | VENTANA MEDICAL SYSTEMS, INC. | 2010-06-03 | — | — | US | disclosed |
| US-20100136652-A1 | Molecular Conjugate | VENTANA MEDICAL SYSTEMS, INC. | 2010-06-03 | — | — | US | disclosed |
| US-20070117153-A1 | Molecular conjugate | VENTANA MEDICAL SYSTEMS, INC. | 2007-05-24 | — | — | US | disclosed |