Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 8/20 | 0.61 |
| ▸ | SRC | P12931 | 5/20 | 0.61 |
| ▸ | INSR | P06213 | 4/20 | 0.61 |
| ▸ | LCK | P06239 | 4/20 | 0.61 |
| ▸ | LYN | P07948 | 4/20 | 0.61 |
| ▸ | KDR | P35968 | 4/20 | 0.61 |
| ▸ | NR2C2 | P49116 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.45 |
| ▸ | FES | P07332 | 1/20 | 0.45 |
| ▸ | FER | P16591 | 1/20 | 0.45 |
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13301722 | 0.94 | LYN (0.54) | HCKSRCINSRLCKLYN | |
| SCHEMBL1824771 | 0.90 | HCK (0.63) | HCKSRCINSRLCKLYN | |
| SCHEMBL13302014 | 0.89 | HCK (0.53) | HCKSRCINSRLCKLYN | |
| SCHEMBL13301899 | 0.89 | HCK (0.48) | HCKSRCINSRLCKLYN | |
| SCHEMBL1841758 | 0.85 | BRAF (0.61) | SRCLYN | |
| SCHEMBL13269773 | 0.84 | LYN (0.62) | HCKSRCINSRLCKLYN | |
| SCHEMBL13301721 | 0.83 | MAPK14 (0.50) | HCKSRCINSRLCKLYN | |
| SCHEMBL13301943 | 0.83 | BRAF (0.51) | HCKSRCINSRLCKLYN | |
| SCHEMBL13291960 | 0.83 | BRAF (0.56) | HCKSRCINSRLCKLYN | |
| SCHEMBL13269709 | 0.83 | CSF1R (0.55) | HCKSRCINSRLCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745437-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2010-06-29 | — | — | US | disclosed |