SCHEMBL13302004

SCHEMBL13302004

Cc1cc(N=C2C(=O)c3cccc4cccc2c34)cc(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR3 O60755 7/20 0.43
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTR4 Q13639 1/20 0.40
CES2 O00748 1/20 0.40
BCHE P06276 1/20 0.40
CES1 P23141 1/20 0.40
MCL1 Q07820 1/20 0.40
CYP3A4 P08684 2/20 0.36
PABPC1 P11940 1/20 0.36
DNMT1 P26358 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13292110 0.91 ALDH1A1 (0.46) GALR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL13292101 0.81 ALDH1A1 (0.47) GALR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL14074360 0.81 ALDH1A1 (0.41) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL2230200 0.74 MEN1 (0.51) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL2230195 0.74 MEN1 (0.51) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL15626043 0.71 GALR3 (0.35) GALR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL29283592 0.71 ALDH1A1 (0.57) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL3804209 0.70 ALDH1A1 (0.44) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL3804212 0.70 ALDH1A1 (0.44) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL13292074 0.70 GALR3 (0.47) GALR3ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7745083-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-06-29 US disclosed
US-20090297218-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-12-03 US disclosed