SCHEMBL1330243

SCHEMBL1330243

NC(Cc1ccccc1)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.56
ACE P12821 3/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 1/20 0.56
MAPK1 P28482 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
ECE1 P42892 1/20 0.56
BLM P54132 1/20 0.56
NPEPPS P55786 1/20 0.56
KMT2A Q03164 1/20 0.56
SLC15A1 P46059 1/20 0.54
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
LTA4H P09960 1/20 0.51
OPRD1 P41143 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1330246 1.00 MME (0.56) MMEACEALDH1A1HPGDMAPK1
SCHEMBL30053224 1.00 MME (0.56) MMEACEALDH1A1HPGDMAPK1
SCHEMBL30760629 1.00 MME (0.56) MMEACEALDH1A1HPGDMAPK1
SCHEMBL1329817 0.94 MME (0.62) MMEACEALDH1A1HPGDMAPK1
SCHEMBL6047673 0.94 MME (0.62) MMEACEALDH1A1HPGDMAPK1
SCHEMBL1329815 0.94 MME (0.62) MMEACEALDH1A1HPGDMAPK1
Hydrochloric Acid SCHEMBL8692954 0.92 MME (0.60) MMEACEALDH1A1HPGDMAPK1
Hydrochloric Acid SCHEMBL8692950 0.92 MME (0.60) MMEACEALDH1A1HPGDMAPK1
SCHEMBL26605058 0.90 ALPI (0.51) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL26605063 0.90 ALPI (0.51) SLC15A1ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108976976-A A kind of environment protecting water-based paint and preparation method thereof 宁波帝杨电子科技有限公司 2018-12-11 CN claimed
CN-108178266-A A kind of efficient sewage treatment flocculant and preparation method thereof 王欣欣 2018-06-19 CN claimed
CN-102300870-B Low molecular weight polysulfated hyaluronic acid derivatives and medicines containing the same OTSUKA CHEMICAL CO LTD 2014-12-03 CN claimed
CN-113480597-B ACE inhibitory peptide derived from perilla seed meal as well as preparation method and application thereof 福州大学 2023-01-10 CN disclosed
CN-113480597-A ACE inhibitory peptide derived from perilla seed meal as well as preparation method and application thereof 福州大学 2021-10-08 CN disclosed
CN-108645804-A A kind of reagent for testing angiotonin converzyme box 金华市强盛生物科技有限公司 2018-10-12 CN disclosed
CN-108178266-A A kind of efficient sewage treatment flocculant and preparation method thereof 王欣欣 2018-06-19 CN disclosed
EP-2392579-B1 LOW-MOLECULAR POLYSULFATED HYALURONIC ACID DERIVATIVE AND MEDICINE CONTAINING SAME OTSUKA CHEMICAL CO LTD (JP) 2016-11-23 EP disclosed
US-8993536-B2 Low-molecular polysulfated hyaluronic acid derivative and medicine containing same OTSUKA CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
CN-102300870-B Low molecular weight polysulfated hyaluronic acid derivatives and medicines containing the same OTSUKA CHEMICAL CO LTD 2014-12-03 CN disclosed
CN-102300870-A Low molecular weight polysulfated hyaluronic acid derivatives and medicines containing the same 2011-12-28 CN disclosed
EP-2392579-A1 LOW-MOLECULAR POLYSULFATED HYALURONIC ACID DERIVATIVE AND MEDICINE CONTAINING SAME Otsuka Chemical Holdings Co., Ltd. (JP) 2011-12-07 EP disclosed
US-20110281819-A1 LOW-MOLECULAR POLYSULFATED HYALURONIC ACID DERIVATIVE AND MEDICINE CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2011-11-17 US disclosed
CN-1693878-A Method and kit for scaling investigating angiotensin aminopherase ZHEJIANG YAKE PHARMACEUTICAL C (CN) 2005-11-09 CN disclosed
CN-1127513-C Phosphonic acid derivatives with metallopeptidase inhibitory activity ZAMBON SPA (IT) 2003-11-12 CN disclosed
EP-0636886-B1 A calibrator or control composition for an IgM serology assay BEHRING DIAGNOSTICS INC (US) 2000-08-30 EP disclosed
CN-1202901-A Phosphonic acid derivatives with metallopeptidase inhibitory activity ZAMBON SPA (IT) 1998-12-23 CN disclosed
US-5478753-A Solution of composite antibody of nonspecific immunoglobulin M covalently bound to specific non-immunoglobulin M antibody directed against specific infectious disease agent PB DIAGNOSTIC SYSTEMS, INC. (US) 1995-12-26 US disclosed
EP-0636886-A2 A calibrator or control composition for an IgM serology assay BEHRING DIAGNOSTICS INC. (US) 1995-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110281819-A1 LOW-MOLECULAR POLYSULFATED HYALURONIC ACID DERIVATIVE AND MEDICINE CONTAINING SAME HRH1, HRH2, HRH3 MME 1361/4885ACE 2807/4885ALDH1A1 1422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.