Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.62 |
| ▸ | ACE | P12821 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1329815 | 1.00 | MME (0.62) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL1329817 | 1.00 | MME (0.62) | MMEACEALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL8692954 | 0.98 | MME (0.60) | MMEACEALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL8692950 | 0.98 | MME (0.60) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL30053224 | 0.94 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL1330243 | 0.94 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL1330246 | 0.94 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL30760629 | 0.94 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL12201779 | 0.88 | ALPI (0.58) | ACESLC15A1ALPIPKMPTGS1 | |
| SCHEMBL8789703 | 0.88 | ALPI (0.58) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100544769-C | Comprise the liquid preparation of camptothecin derivative and the pharmaceutical composition that the lyophilizing said preparation makes | TANABE SEIYAKU CO (JP) | 2009-09-30 | — | — | CN | claimed |
| CN-100372570-C | Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence of maligant tumor | TANABE SEIYAKU CO (JP) | 2008-03-05 | — | — | CN | claimed |
| US-20060052288-A1 | Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-03-09 | — | — | US | claimed |
| US-20050215485-A1 | Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-09-29 | — | — | US | claimed |
| CN-1646172-A | Liquid preparation containing camptothecin derivative and pharmaceutical composition prepared by freeze-drying the preparation | TANABE SEIYAKU CO (JP) | 2005-07-27 | — | — | CN | claimed |
| EP-1501549-A2 | LYOPHILISED AND LIQUID PREPARATIONS COMPRISING A POLYSACCHARIDE DERIVATIVE OF CAMPTOTHECIN | TANABE SEIYAKU CO., LTD. (JP) | 2005-02-02 | — | — | EP | claimed |
| CN-1545423-A | Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence of maligant tumor | ������ҩ��ʽ���� | 2004-11-10 | — | — | CN | claimed |
| EP-1418947-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSACCHARIDE CONJUGATES FOR INHIBITING THE METASTASIS OR PREVENTING THE RECURRENCE OF MALIGNANT TUMOR | TANABE SEIYAKU CO., LTD. (JP) | 2004-05-19 | — | — | EP | claimed |
| CN-1142935-C | Comptothecin compounds and preparation thereof | ������ҩ��ʽ���� | 2004-03-24 | — | — | CN | claimed |
| WO-2003086471-A2 | LYOPHILIZED AND LIQUID PREPARATIONS COMPRISING A POLYSACCHARIDE DERIVATIVE OF CAMPTOTHECIN | TANABE SEIYAKU CO., LTD. (JP) | 2003-10-23 | — | — | WO | claimed |
| CN-1075501-C | Camptothecin derivatives, preparation method, intermediate and application | TANABE SEIYAKU CO (JP) | 2001-11-28 | — | — | CN | claimed |
| CN-1073113-C | Camptothecin derivative and preparation method and application thereof | TANABE SEIYAKU CO (JP) | 2001-10-17 | — | — | CN | claimed |
| EP-0781781-B1 | Camptothecin derivatives | TANABE SEIYAKU CO (JP) | 2001-10-10 | — | — | EP | claimed |
| CN-1300733-A | Comptothecin compounds and preparation thereof | TANABE SEIYAKU CO (JP) | 2001-06-27 | — | — | CN | claimed |
| US-5892043-A | MIXTURE WITH POLYSACCHARIDE AND PEPTIDE; ANTITUMOR AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1999-04-06 | — | — | US | claimed |
| EP-0757049-B1 | Camptothecin derivatives | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | claimed |
| US-5837673-A | ANTITUMOR AGENTS AND ANTICARCINOGENIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-17 | — | — | US | claimed |
| CN-1158334-A | Camptothecin derivatives | TANABE SEIYAKU CO (JP) | 1997-09-03 | — | — | CN | claimed |
| EP-0781781-A2 | Camptothecin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1997-07-02 | — | — | EP | claimed |
| EP-0757049-A1 | Camptothecin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1997-02-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052288-A1 | Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor | CD44, MUC1, HGFAC | MME 52/4885ACE 753/4885ALDH1A1 4169/4885 |
| US-20050215485-A1 | Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation | ALK, ACVR1, ACVR1B | MME 4615/4885ACE 3968/4885ALDH1A1 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.