SCHEMBL13304403

SCHEMBL13304403

Cc1ccc2nc(C)c(S(N)(=O)=O)n2n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TNF P01375 1/20 0.34
AKT1 P31749 1/20 0.33
AKT2 P31751 1/20 0.33
CA12 O43570 7/20 0.32
CA1 P00915 7/20 0.32
CA2 P00918 7/20 0.32
CA9 Q16790 7/20 0.32
PKM P14618 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
CA3 P07451 2/20 0.31
CA6 P23280 2/20 0.31
CA5A P35218 2/20 0.31
CA7 P43166 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3347966 0.85 TNF (0.51) KDM4EMEN1KMT2ATNFAKT1
SCHEMBL3342264 0.84 AKT1 (0.39) KDM4ETNFAKT1AKT2MAPT
SCHEMBL9517415 0.83 NOTUM (0.32) TNFPKMALDH1A1SMN1; SMN2
SCHEMBL3346096 0.83 MEN1 (0.38) KDM4EMEN1KMT2ATNFAKT1
SCHEMBL3169997 0.83 AKT1 (0.35) TNFAKT1AKT2CA12CA1
SCHEMBL2066401 0.83 ALDH1A1 (0.32) TNFPKMALDH1A1SMN1; SMN2
SCHEMBL3344359 0.83 KDM4E (0.35) KDM4EMEN1KMT2ATNFAKT1
SCHEMBL9518763 0.83 KDM4E (0.41) KDM4EAKT1AKT2CA12CA1
SCHEMBL2066413 0.81 PDE10A (0.38) KDM4ECA12CA1CA2CA9
SCHEMBL2066633 0.79 HPGD (0.43) KDM4EKMT2APOLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399381-B2 Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US disclosed
US-20100160163-A1 Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weed with the same TANAKA YASUSHI 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160163-A1 Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weed with the same NOTUM, WEE1, DDT KDM4E 503/4885MEN1 3853/4885KMT2A 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.