Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 17/20 | 0.65 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953003 | 0.86 | GSK3B (0.87) | GSK3BCDK2CCNE1 | |
| SCHEMBL13146320 | 0.86 | GSK3B (0.68) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14613385 | 0.83 | GSK3B (0.57) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL12954066 | 0.83 | GSK3B (0.61) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14418669 | 0.82 | GSK3B (0.56) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13122093 | 0.81 | GSK3B (0.78) | GSK3BCDK2CCNE1 | |
| SCHEMBL13305383 | 0.81 | GSK3B (0.56) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL12954477 | 0.81 | GSK3B (0.63) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL12953330 | 0.81 | GSK3B (0.80) | GSK3BCDK2CCNE1 | |
| SCHEMBL13304782 | 0.80 | GSK3B (0.72) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537116-B1 | PYRAZOLOPYRIMIDINES SUITABLE FOR THE TREATMENT OF CANCER DISEASES | SCHERING CORP (US) | 2010-06-02 | — | — | EP | disclosed |