Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | EEF2K | O00418 | 2/20 | 0.32 |
| ▸ | EEF2 | P13639 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL1329515 | 0.94 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1329196 | 0.94 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1329427 | 0.94 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1330923 | 0.94 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| Dichloroacetic Acid SCHEMBL28651964 | 0.89 | CA1 (0.43) | CA1CA2EEF2KEEF2MEN1 | |
| Acetic Acid SCHEMBL15392706 | 0.88 | CA1 (0.47) | CA1CA2EEF2KEEF2MEN1 | |
| Bicarbonate SCHEMBL28901538 | 0.88 | CA1 (0.47) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1331540 | 0.87 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL22832298 | 0.84 | CA1 (0.43) | CA1CA2EEF2KEEF2MEN1 | |
| Butyric Acid SCHEMBL18037730 | 0.84 | CA1 (0.43) | CA1CA2EEF2KEEF2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8730559-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20110279885-A1 | MULTICOLOR DISPLAY OPTICAL COMPOSITION, OPTICAL DEVICE, AND DISPLAY METHOD OF OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| US-8023176-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100188732-A1 | MULTICOLOR DISPLAY OPTICAL COMPOSITION, OPTICAL DEVICE, AND DISPLAY METHOD OF OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-7746542-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7724433-B2 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7538933-B2 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070121193-A1 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. | 2007-05-31 | — | — | US | disclosed |
| US-20070115550-A1 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-20070008439-A1 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| EP-1734402-A2 | Optical arrangement having a periodic structural body for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2006-12-20 | — | — | EP | disclosed |