Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dichloroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | EEF2K | O00418 | 2/20 | 0.32 |
| ▸ | EEF2 | P13639 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL1330664 | 0.89 | CA1 (0.43) | CA1CA2EEF2KEEF2MEN1 | |
| Bicarbonate SCHEMBL28901538 | 0.88 | CA1 (0.47) | CA1CA2EEF2KEEF2MEN1 | |
| Acetic Acid SCHEMBL15392706 | 0.88 | CA1 (0.47) | CA1CA2EEF2KEEF2MEN1 | |
| Butyric Acid SCHEMBL18037730 | 0.84 | CA1 (0.43) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL22832298 | 0.84 | CA1 (0.43) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1330923 | 0.83 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1329427 | 0.83 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1329196 | 0.83 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| L-Lactic Acid SCHEMBL1329515 | 0.83 | CA1 (0.50) | CA1CA2EEF2KEEF2MEN1 | |
| Trifluoroacetic Acid SCHEMBL4352925 | 0.83 | CA1 (0.43) | CA1CA2EEF2KEEF2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631136-A | Primer and kit of primer and dental material | 凯滕巴赫股份两合公司 | 2021-11-09 | — | — | CN | disclosed |