Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | EEF2K | O00418 | 2/20 | 0.44 |
| ▸ | EEF2 | P13639 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1330217 | 1.00 | CA1 (0.59) | CA1CA2MEN1KMT2AEEF2K | |
| Hydrochloric Acid SCHEMBL1330556 | 1.00 | CA1 (0.59) | CA1CA2MEN1KMT2AEEF2K | |
| Hydrochloric Acid SCHEMBL2952424 | 1.00 | CA1 (0.59) | CA1CA2MEN1KMT2AEEF2K | |
| Hydrochloric Acid SCHEMBL1501538 | 1.00 | CA1 (0.59) | CA1CA2MEN1KMT2AEEF2K | |
| Hydrochloric Acid SCHEMBL385260 | 1.00 | CA1 (0.59) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL1826848 | 0.98 | CA1 (0.61) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL4059675 | 0.98 | CA1 (0.61) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL372253 | 0.98 | CA1 (0.61) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL5287243 | 0.98 | CA1 (0.61) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL4070935 | 0.98 | CA1 (0.61) | CA1CA2MEN1KMT2AEEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310528-A1 | DEEP EUTECTIC SOLVENT INCLUDING ONE OR MORE ACTIVE PHARMACEUTICAL INGREDIENTS DERIVED FROM MUSHROOMS | OPTIMI HEALTH CORP (CA) | 2023-10-05 | — | — | US | disclosed |
| US-8730559-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20110279885-A1 | MULTICOLOR DISPLAY OPTICAL COMPOSITION, OPTICAL DEVICE, AND DISPLAY METHOD OF OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| US-8023176-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100188732-A1 | MULTICOLOR DISPLAY OPTICAL COMPOSITION, OPTICAL DEVICE, AND DISPLAY METHOD OF OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-7746542-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7724433-B2 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7538933-B2 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD (JP) | 2009-05-26 | — | — | US | disclosed |
| US-7455903-B2 | Optical materials and optical elements using the same | FUJI XEROX CO., LTD. (JP) | 2008-11-25 | — | — | US | disclosed |
| EP-1697465-B1 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GEN ELECTRIC (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20070121193-A1 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. | 2007-05-31 | — | — | US | disclosed |
| US-20070115550-A1 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-20070008439-A1 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| EP-1734402-A2 | Optical arrangement having a periodic structural body for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1697465-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20060121285-A1 | Optical materials and optical elements using the same | FUJI XEROX CO., LTD. | 2006-06-08 | — | — | US | disclosed |
| WO-2005061623-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050137310-A1 | Polymer nanocomposites and methods for their preparation | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-06-23 | — | — | US | disclosed |