Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14330850 | 0.99 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDNPC1RAB9ARECQL | |
| SCHEMBL13307358 | 0.97 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDNPC1RAB9ARECQL | |
| SCHEMBL14129503 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDNPC1RAB9ARECQL | |
| SCHEMBL14129348 | 0.94 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDNPC1RAB9ARECQL | |
| SCHEMBL16510003 | 0.94 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDNPC1RAB9ARECQL | |
| SCHEMBL14129350 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDNPC1RAB9ACA2 | |
| SCHEMBL12173390 | 0.89 | BRD4 (0.46) | SMN1; SMN2HPGDNPC1RAB9AGAA | |
| SCHEMBL14129352 | 0.88 | BRD4 (0.47) | SMN1; SMN2HPGDNPC1RAB9AGAA | |
| SCHEMBL12268002 | 0.87 | BRD4 (0.44) | HPGDNPC1RAB9AGAABRD4 | |
| SCHEMBL24943212 | 0.87 | MAPT (0.42) | SMN1; SMN2HPGDNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8728520-B2 | Cross-linked alginate-polyalkylene glycol polymer coatings for encapsulation and methods of making the same | UNIVERSITY OF MIAMI (US) | 2014-05-20 | — | — | US | disclosed |
| US-20100143464-A1 | CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME | UNIVERSITY OF MIAMI | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143464-A1 | CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME | ALG1, PAG1, GALR3 | SMN1; SMN2 3867/4885HPGD 1386/4885NPC1 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.