SCHEMBL14129348

SCHEMBL14129348

COC(=O)c1ccc(C(=O)NCCOCCOCCN)cc1P(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
CA2 P00918 4/20 0.41
HPGD P15428 2/20 0.41
PRKCD Q05655 1/20 0.39
CAMK2B Q13554 1/20 0.39
CAMK2G Q13555 1/20 0.39
AURKB Q96GD4 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
BRD4 O60885 2/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
RECQL P46063 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38
TP53 P04637 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NAMPT P43490 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16510003 1.00 SMN1; SMN2 (0.47) SMN1; SMN2CA2HPGDPRKCDCAMK2B
SCHEMBL14129503 0.99 SMN1; SMN2 (0.45) SMN1; SMN2CA2HPGDPRKCDCAMK2B
SCHEMBL14330850 0.95 SMN1; SMN2 (0.52) SMN1; SMN2CA2HPGDBRD4NPC1
SCHEMBL13307352 0.94 SMN1; SMN2 (0.50) SMN1; SMN2CA2HPGDBRD4NPC1
SCHEMBL13307358 0.91 SMN1; SMN2 (0.47) SMN1; SMN2CA2HPGDNPC1RAB9A
SCHEMBL20919156 0.91 SMN1; SMN2 (0.50) SMN1; SMN2CA2HPGDPRKCDCAMK2B
SCHEMBL14129352 0.89 BRD4 (0.47) SMN1; SMN2HPGDBRD4NPC1RAB9A
SCHEMBL10191049 0.86 BRD4 (0.45) BRD4NPC1RAB9AMEN1KMT2A
SCHEMBL14129350 0.86 SMN1; SMN2 (0.44) SMN1; SMN2CA2HPGDBRD4NPC1
SCHEMBL15076060 0.85 BRD4 (0.45) HDAC3HDAC1BRD4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3697404-B1 COMPOSITIONS AND METHODS FOR BROAD-SPECTRUM ANTIVIRAL THERAPY VERSITECH LTD (HK) 2025-03-26 EP disclosed
US-12213955-B2 Compositions and methods for broad-spectrum antiviral therapy VERSITECH LIMITED (CN) 2025-02-04 US disclosed
CN-111886008-B Compositions and methods for anti-MERS-coronavirus therapy 港大科桥有限公司 2024-05-31 CN disclosed
CN-111886008-A Compositions and methods for broad spectrum antiviral therapy 阿瓦隆黄病毒治疗(香港)有限公司 2020-11-03 CN disclosed
US-20200338032-A1 COMPOSITIONS AND METHODS FOR BROAD-SPECTRUM ANTIVIRAL THERAPY VERSITECH LIMITED (CN) 2020-10-29 US disclosed
US-20080181847-A1 Targeted Imaging and/or Therapy Using the Staudinger Ligation KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-07-31 US disclosed
US-20080181847-A1 Targeted Imaging and/or Therapy Using the Staudinger Ligation KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080181847-A1 Targeted Imaging and/or Therapy Using the Staudinger Ligation BTD, HLCS, BOLA2; BOLA2B SMN1; SMN2 2929/4885CA2 4599/4885HPGD 2259/4885
US-20200338032-A1 COMPOSITIONS AND METHODS FOR BROAD-SPECTRUM ANTIVIRAL THERAPY MAVS, RARB, RARG SMN1; SMN2 4086/4885CA2 4852/4885HPGD 4038/4885
US-12213955-B2 Compositions and methods for broad-spectrum antiviral therapy MAVS, RARB, RARG SMN1; SMN2 4099/4885CA2 4856/4885HPGD 3998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.