Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.44 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.44 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13307705 | 0.88 | POLB (0.53) | POLBMAPTCNR1HSP90AA1HSP90B1 | |
| SCHEMBL13307617 | 0.88 | POLB (0.53) | POLBMAPTCNR1HSP90AA1HSP90B1 | |
| SCHEMBL13307703 | 0.87 | POLB (0.52) | POLBMAPTCNR1HSP90AA1HSP90B1 | |
| SCHEMBL13307618 | 0.87 | CNR1 (0.49) | POLBMAPTCNR1HSP90AA1HSP90B1 | |
| SCHEMBL13307580 | 0.86 | CNR1 (0.49) | POLBMAPTCNR1HSP90AA1HSP90B1 | |
| SCHEMBL13307613 | 0.85 | CNR1 (0.49) | POLBMAPTCNR1HSP90AA1HSP90B1 | |
| SCHEMBL13307642 | 0.85 | POLB (0.52) | POLBMAPTCNR1HSP90AA1L3MBTL1 | |
| SCHEMBL13307598 | 0.84 | CNR1 (0.52) | POLBMAPTCNR1HSP90AA1HSP90B1 | |
| SCHEMBL13307565 | 0.84 | POLB (0.58) | POLBMAPTHSP90AA1L3MBTL1GAA | |
| SCHEMBL13307611 | 0.81 | CNR1 (0.48) | POLBMAPTCNR1HSP90AA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293773-B2 | 1, 2, 3-triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-10-23 | — | — | US | disclosed |
| US-8293773-B2 | 1, 2, 3-triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-10-23 | — | — | US | disclosed |
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-06-10 | — | — | US | disclosed |
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | CNR1, CNR2, GPR3 | POLB 4840/4885MAPT 2428/4885CNR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.