Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.53 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.53 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL1331139 | 0.93 | ACHE (0.65) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Cetylpyridinium SCHEMBL28815637 | 0.91 | KMT2A (0.64) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Cetylpyridinium SCHEMBL28519379 | 0.91 | ACHE (0.61) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Bicarbonate SCHEMBL28058344 | 0.87 | ACHE (0.63) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Acetic Acid SCHEMBL4538473 | 0.85 | ACHE (0.61) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Propionic Acid SCHEMBL1006275 | 0.84 | ACHE (0.59) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Bicarbonate SCHEMBL28058346 | 0.83 | ACHE (0.68) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| L-Lactic Acid SCHEMBL1328758 | 0.82 | KMT2A (0.37) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Acetic Acid SCHEMBL28281286 | 0.81 | ACHE (0.65) | ACHECHRM2ADRA2AADORA3CHRM1 | |
| Butyric Acid SCHEMBL2788853 | 0.81 | CHRM2 (0.55) | ACHECHRM2ADRA2AADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8730559-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20110279885-A1 | MULTICOLOR DISPLAY OPTICAL COMPOSITION, OPTICAL DEVICE, AND DISPLAY METHOD OF OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| US-8023176-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100188732-A1 | MULTICOLOR DISPLAY OPTICAL COMPOSITION, OPTICAL DEVICE, AND DISPLAY METHOD OF OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-7746542-B2 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7724433-B2 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7538933-B2 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD (JP) | 2009-05-26 | — | — | US | disclosed |
| CN-100476562-C | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| US-7455903-B2 | Optical materials and optical elements using the same | FUJI XEROX CO., LTD. (JP) | 2008-11-25 | — | — | US | disclosed |
| US-20070121193-A1 | Multicolor display optical composition, optical device, and display method of optical device | FUJI XEROX CO., LTD. | 2007-05-31 | — | — | US | disclosed |
| CN-1971393-A | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO LTD (JP) | 2007-05-30 | — | — | CN | disclosed |
| US-20070115550-A1 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-20070008439-A1 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| EP-1734402-A2 | Optical arrangement having a periodic structural body for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-20060121285-A1 | Optical materials and optical elements using the same | FUJI XEROX CO., LTD. | 2006-06-08 | — | — | US | disclosed |