Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13307771 | 0.89 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL13307734 | 0.82 | CNR1 (0.69) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL5050317 | 0.77 | CNR1 (0.67) | CNR1ALDH1A1POLBMAPTALOX15 | |
| SCHEMBL5909566 | 0.74 | CNR1 (0.60) | CNR1CNR2NPC1RAB9AL3MBTL1 | |
| SCHEMBL13307752 | 0.73 | AURKA (0.50) | CNR1LMNACNR2NPC1RAB9A | |
| SCHEMBL13307870 | 0.73 | CNR1 (0.92) | CNR1CNR2 | |
| SCHEMBL4832493 | 0.72 | CNR1 (0.47) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL4076305 | 0.71 | CNR1 (1.00) | CNR1 | |
| SCHEMBL7089994 | 0.71 | CNR1 (0.81) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL4457218 | 0.71 | CNR1 (1.00) | CNR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293773-B2 | 1, 2, 3-triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-10-23 | — | — | US | disclosed |
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | CNR1, CNR2, GPR3 | CNR1 1/4885ALDH1A1 2585/4885SMN1; SMN2 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.