SCHEMBL1330795

SCHEMBL1330795

[13CH3]Cc1ccc(C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
RXRA P19793 2/20 0.69
RXRB P28702 2/20 0.69
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
PLK1 P53350 1/20 0.59
BCL2 P10415 1/20 0.58
RARB P10826 6/20 0.57
TAS2R14 Q9NYV8 1/20 0.56
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.53
SRD5A2 P31213 2/20 0.53
KDM4E B2RXH2 1/20 0.53
USP2 O75604 1/20 0.53
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1330335 1.00 ALDH1A1 (1.00) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL19901 1.00 ALDH1A1 (1.00) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL6913296 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL6911296 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL6915465 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL6909050 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL6909401 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL2590166 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR
Ammonia Solution, Strong SCHEMBL22042012 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR
SCHEMBL8972050 0.98 ALDH1A1 (0.95) ALDH1A1RXRARXRBTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 US disclosed