Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13308036 | 0.96 | CNR1 (0.73) | CNR1TSHRCNR2TAS1R3TAS1R1 | |
| SCHEMBL13308000 | 0.89 | CNR1 (0.69) | CNR1TSHRCNR2 | |
| SCHEMBL13307870 | 0.86 | CNR1 (0.92) | CNR1CNR2 | |
| SCHEMBL13307976 | 0.85 | CNR1 (0.63) | CNR1TSHRCNR2 | |
| SCHEMBL13307957 | 0.84 | CNR1 (0.74) | CNR1CNR2 | |
| SCHEMBL13307825 | 0.81 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL13308040 | 0.79 | CNR1 (0.80) | CNR1CNR2 | |
| SCHEMBL13307993 | 0.77 | CNR1 (0.60) | CNR1TSHR | |
| SCHEMBL13307879 | 0.76 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL13307945 | 0.76 | CNR1 (0.59) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293773-B2 | 1, 2, 3-triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-10-23 | — | — | US | disclosed |
| US-8293773-B2 | 1, 2, 3-triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-10-23 | — | — | US | disclosed |
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-06-10 | — | — | US | disclosed |
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144734-A1 | 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists | CNR1, CNR2, GPR3 | CNR1 1/4885TSHR 722/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.