SCHEMBL13307995

SCHEMBL13307995

O=C(Cn1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1)NC1CCN(Cc2ccccc2)CC1

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 8/20 0.66
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
SIGMAR1 Q99720 5/20 0.61
SLC6A12 P48065 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13307870 0.85 CNR1 (0.92) CNR1
SCHEMBL13307957 0.83 CNR1 (0.74) CNR1
SCHEMBL13307959 0.80 CNR1 (1.00) CNR1
SCHEMBL13308040 0.78 CNR1 (0.80) CNR1KMT2A
SCHEMBL13308048 0.78 CNR1 (0.81) CNR1
SCHEMBL13307945 0.77 CNR1 (0.59) CNR1MEN1KMT2A
SCHEMBL5050317 0.77 CNR1 (0.67) CNR1MEN1KMT2A
SCHEMBL13308000 0.76 CNR1 (0.69) CNR1
SCHEMBL13308053 0.76 CNR1 (0.78) CNR1
SCHEMBL13307993 0.76 CNR1 (0.60) CNR1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293773-B2 1, 2, 3-triazole derivatives as new cannabinoid-1 receptor antagonists NATIONAL TSING HUA UNIVERSITY (TW) 2012-10-23 US disclosed
US-8293773-B2 1, 2, 3-triazole derivatives as new cannabinoid-1 receptor antagonists NATIONAL TSING HUA UNIVERSITY (TW) 2012-10-23 US disclosed
US-20100144734-A1 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists NATIONAL TSING HUA UNIVERSITY (TW) 2010-06-10 US disclosed
US-20100144734-A1 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists NATIONAL TSING HUA UNIVERSITY (TW) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144734-A1 1, 2, 3-Triazole derivatives as new cannabinoid-1 receptor antagonists CNR1, CNR2, GPR3 CNR1 1/4885MEN1 2978/4885KMT2A 3239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.