Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920540 | 0.91 | NT5E (0.50) | NT5ECA9CA1CA2CYP2D6 | |
| SCHEMBL12871737 | 0.88 | NT5E (0.45) | NT5ECA9CA1CA2CYP2D6 | |
| SCHEMBL14409792 | 0.86 | CYP2D6 (0.54) | CA9CA1CA2CYP2D6ALDH1A1 | |
| SCHEMBL1582789 | 0.86 | CYP2D6 (0.54) | CA9CA1CA2CYP2D6ALDH1A1 | |
| SCHEMBL12871706 | 0.86 | NT5E (0.49) | NT5EPTPN1CDC25B | |
| SCHEMBL13775076 | 0.86 | CYP2D6 (0.42) | NT5ECA9CA1CA2CYP2D6 | |
| SCHEMBL29220838 | 0.84 | CYP2D6 (0.51) | NT5ECA9CA1CA2CYP2D6 | |
| SCHEMBL29220835 | 0.84 | CYP2D6 (0.51) | NT5ECA9CA1CA2CYP2D6 | |
| SCHEMBL12920538 | 0.84 | NT5E (0.51) | NT5EPOLBKMT2APTPN1CDC25B | |
| SCHEMBL13775020 | 0.83 | TSHR (0.53) | CA9CA1CA2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728106-B2 | HIV-1 glycopeptides and derivatives; preparation and applications thereof | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070224211-A1 | HIV-1 glycopeptides and derivatives; preparation and applications thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224211-A1 | HIV-1 glycopeptides and derivatives; preparation and applications thereof | ENGASE, GALE, CD4 | NT5E 1125/4885CA9 2931/4885CA1 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.