Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14409792 | 1.00 | CYP2D6 (0.54) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL12920544 | 0.94 | TSHR (0.58) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL9853889 | 0.94 | CYP2D6 (0.49) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL9853901 | 0.94 | CYP2D6 (0.49) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL17502007 | 0.91 | LMNA (0.58) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL17502010 | 0.91 | LMNA (0.58) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL29709612 | 0.91 | LMNA (0.58) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL23742930 | 0.91 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL15514610 | 0.91 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL8722654 | 0.91 | TSHR (0.64) | CYP2D6ALDH1A1MAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637578-B2 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins | ISIS INNOVATION LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |
| EP-1644390-B1 | REAGENTS AND METHODS FOR THE FORMATION OF DISULFIDE BONDS AND THE GLYCOSYLATION OF PROTEINS | ISIS INNOVATION (GB) | 2011-04-20 | — | — | EP | disclosed |
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | ISIS INNOVATION LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | SCLY, PTMS, TST | CYP2D6 3084/4885ALDH1A1 3136/4885MAPK1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.