Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.39 |
| ▸ | TXK | P42681 | 1/20 | 0.39 |
| ▸ | BMX | P51813 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070135 | 0.90 | HTT (0.46) | POLBHTTL3MBTL1GRIN1GRIN2B | |
| SCHEMBL13308563 | 0.86 | EGLN2 (0.39) | POLBHTTL3MBTL1ARGAA | |
| SCHEMBL13308971 | 0.82 | CYP1A2 (0.43) | HTTARGAAMAPT | |
| SCHEMBL3084002 | 0.82 | AR (0.48) | L3MBTL1GRIN1GRIN2BAR | |
| SCHEMBL13309099 | 0.81 | FNTA (0.43) | POLBARGAANPSR1 | |
| SCHEMBL13308619 | 0.81 | POLB (0.45) | POLBARPTGDR2GAANPSR1 | |
| SCHEMBL3076403 | 0.80 | AR (0.47) | ARPTGDR2 | |
| SCHEMBL13309112 | 0.80 | MBOAT4 (0.39) | ARCNR1 | |
| SCHEMBL3085333 | 0.79 | AR (0.42) | POLBHTTL3MBTL1AR | |
| SCHEMBL3069365 | 0.79 | AR (0.48) | ARPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194045-A1 | SUBSTITUTED PYRAZOLE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2010-06-09 | — | — | EP | disclosed |