SCHEMBL13308448

SCHEMBL13308448

Cc1ccc(N(c2ccc(CCc3ccc(CCc4ccc(N(c5ccc(C)cc5)c5c(C)cc(C)cc5C)cc4)cc3)cc2)c2c(C)cc(C)cc2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CALM1 P0DP23 1/20 0.40
KCNH2 Q12809 1/20 0.39
FFAR4 Q5NUL3 1/20 0.38
ALOX15 P16050 2/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
IGF1R P08069 1/20 0.38
DAO P14920 2/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.36
CHKA P35790 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
NR3C2 P08235 1/20 0.36
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12018763 0.88 ALDH1A1 (0.46) CYP1A2CYP2A6FFAR4ALDH1A1TSHR
SCHEMBL682063 0.88 ALDH1A1 (0.46) CYP1A2CYP2A6FFAR4ALDH1A1TSHR
SCHEMBL2316061 0.85 BACE1 (0.37) CYP1A2CYP2A6TAAR1FFAR4ALOX15
SCHEMBL13197742 0.84 SKP2 (0.44) CYP1A2KCNH2FFAR4ALOX15IGF1R
SCHEMBL12313694 0.84 SKP2 (0.46) CYP1A2KCNH2FFAR4ALOX15PTGS2
SCHEMBL12313728 0.84 ALDH1A1 (0.42) CYP1A2CYP2A6FFAR4ALDH1A1TSHR
SCHEMBL12313699 0.84 ALDH1A1 (0.42) CYP1A2CYP2A6FFAR4ALDH1A1TSHR
SCHEMBL13197749 0.84 ALDH1A1 (0.42) CYP1A2CYP2A6FFAR4ALDH1A1TSHR
SCHEMBL13197770 0.84 ALDH1A1 (0.42) CYP1A2CYP2A6FFAR4ALDH1A1TSHR
SCHEMBL12313701 0.84 ALDH1A1 (0.42) CYP1A2CYP2A6FFAR4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-20100150606-A1 METHOD OF MANUFACTURING IMAGE BEARING MEMBER, IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-06-17 US disclosed