Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3271349 | 0.81 | HRH3 (0.55) | HRH3ALDH1A1KCNH2 | |
| SCHEMBL3278843 | 0.79 | HRH3 (0.58) | HRH3ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL3275437 | 0.78 | HRH3 (0.61) | HRH3ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL3272759 | 0.78 | HRH3 (0.61) | HRH3ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL3272777 | 0.76 | HRH3 (0.64) | HRH3ALDH1A1LMNACYP1A2MAPK1 | |
| SCHEMBL3277455 | 0.75 | EPHX2 (0.60) | HRH3ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL3270832 | 0.74 | HRH3 (0.61) | HRH3ALDH1A1LMNACYP1A2MAPK1 | |
| Methylamine SCHEMBL5161014 | 0.74 | HRH3 (0.61) | HRH3ALDH1A1LMNACYP1A2MAPK1 | |
| SCHEMBL3270978 | 0.74 | HRH3 (0.61) | HRH3ALDH1A1LMNACYP1A2MAPK1 | |
| SCHEMBL3271106 | 0.74 | HRH3 (0.64) | HRH3ALDH1A1LMNACYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747210-B1 | 3- OR 4-MONOSUBSTITUTED PHENOL AND THIOPHENOL DERIVATIVES USEFUL AS H3 LIGANDS | WARNER LAMBERT CO (US) | 2010-06-30 | — | — | EP | disclosed |