Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286635 | 1.00 | REN (0.52) | REN | |
| SCHEMBL5754839 | 0.92 | REN (0.58) | REN | |
| Hydrochloric Acid SCHEMBL3298976 | 0.91 | REN (0.60) | REN | |
| SCHEMBL3271541 | 0.82 | REN (0.52) | REN | |
| SCHEMBL13344752 | 0.80 | REN (0.60) | REN | |
| SCHEMBL13344746 | 0.80 | REN (0.62) | REN | |
| Hydrochloric Acid SCHEMBL3270996 | 0.79 | REN (0.61) | REN | |
| Hydrochloric Acid SCHEMBL5157404 | 0.79 | REN (0.63) | REN | |
| Hydrochloric Acid SCHEMBL5157410 | 0.79 | REN (0.63) | REN | |
| Hydrochloric Acid SCHEMBL3270990 | 0.79 | REN (0.61) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735270-B1 | DIAMINO ALCOHOLS AND THEIR USE AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2010-06-30 | — | — | EP | disclosed |