Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 5/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837206 | 0.85 | FFAR2 (0.54) | FFAR2KCNH2S1PR5MAOB | |
| SCHEMBL2832359 | 0.85 | FFAR2 (0.54) | FFAR2KCNH2S1PR5MAOB | |
| SCHEMBL2835415 | 0.85 | FFAR2 (0.54) | FFAR2KCNH2S1PR5MAOB | |
| SCHEMBL311160 | 0.85 | FFAR2 (0.49) | FFAR2KCNH2S1PR5PPARG | |
| SCHEMBL840904 | 0.85 | FFAR2 (0.49) | FFAR2KCNH2S1PR5PPARG | |
| SCHEMBL841242 | 0.85 | FFAR2 (0.49) | FFAR2KCNH2S1PR5PPARG | |
| SCHEMBL310672 | 0.81 | KCNH2 (0.59) | FFAR2KCNH2S1PR5PPARGKDM4E | |
| SCHEMBL311548 | 0.81 | KCNH2 (0.59) | FFAR2KCNH2S1PR5PPARGKDM4E | |
| SCHEMBL310922 | 0.81 | KCNH2 (0.59) | FFAR2KCNH2S1PR5PPARGKDM4E | |
| SCHEMBL483621 | 0.81 | KCNH2 (0.59) | FFAR2KCNH2S1PR5PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943216-B1 | PROLINAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS | GLAXO GROUP LTD (GB) | 2010-06-30 | — | — | EP | disclosed |